Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | RET | P07949 | 3/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | DHFR | P00374 | 2/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.33 |
| ▸ | ADK | P55263 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.32 |
| ▸ | IRAK2 | O43187 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.32 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 2/20 | 0.31 |
| ▸ | SRC | P12931 | 2/20 | 0.31 |
| ▸ | TEK | Q02763 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2950069 | 0.75 | ADORA2A (0.49) | HRH3MAP4K4JAK1 | |
| SCHEMBL30465997 | 0.72 | HRH3 (0.43) | HRH3RETKDRMTOR | |
| SCHEMBL19743265 | 0.72 | SRC (0.52) | RETKDRMAP4K4ADKIRAK4 | |
| SCHEMBL29503453 | 0.72 | SRC (0.52) | RETKDRMAP4K4ADKIRAK4 | |
| SCHEMBL1786788 | 0.70 | RET (0.58) | RETKDRMAP4K4ADKCLK2 | |
| SCHEMBL4721622 | 0.68 | SRC (0.59) | RETKDRMAP4K4ADKIRAK4 | |
| SCHEMBL6866172 | 0.68 | SRC (0.59) | RETKDRMAP4K4ADKIRAK4 | |
| SCHEMBL6867797 | 0.68 | SRC (0.59) | RETKDRMAP4K4ADKIRAK4 | |
| Hydrochloric Acid SCHEMBL6868366 | 0.68 | SRC (0.58) | RETKDRMAP4K4ADKIRAK4 | |
| Hydrochloric Acid SCHEMBL6868362 | 0.68 | SRC (0.58) | RETKDRMAP4K4ADKIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060025383-A1 | Aminobenzoxazoles as therapeutic agents | ABBOTT LABORATORIES | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025383-A1 | Aminobenzoxazoles as therapeutic agents | ABL1, MAP3K19, MAP3K20 | HRH3 2750/4885RET 848/4885KDR 2441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.