Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.39 |
| ▸ | MTOR | P42345 | 6/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | PDE9A | O76083 | 6/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.38 |
| ▸ | PDE1A | P54750 | 2/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26102644 | 0.88 | PDE1C (0.46) | PDE9APDE1CPDE1APDE1B | |
| SCHEMBL30455250 | 0.82 | RET (0.49) | RETKDR | |
| SCHEMBL30466007 | 0.80 | ALOX15 (0.54) | PIK3CAMTORPIK3CGMAPK14CSNK1G1 | |
| SCHEMBL3750895 | 0.74 | CDK4 (0.51) | PIK3CAMTOR | |
| SCHEMBL6108014 | 0.72 | HRH3 (0.40) | HRH3MTORRETKDR | |
| SCHEMBL2950069 | 0.72 | ADORA2A (0.49) | HRH3 | |
| SCHEMBL16985541 | 0.71 | IRAK4 (0.41) | RETKDR | |
| SCHEMBL3757216 | 0.71 | CDK4 (0.48) | PIK3CAMTOR | |
| SCHEMBL4392941 | 0.70 | FLT3 (0.47) | PIK3CAMTORPIK3CGMAPK14CSNK1G1 | |
| SCHEMBL30466004 | 0.69 | IGF1R (0.49) | RETKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023128708-A1 | PYRAZOLOPYRIMIDINE DERIVATIVE AND ANTICANCER PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | 한국화학연구원 | 2023-07-06 | — | — | WO | disclosed |