Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.56 |
| ▸ | CTSB | P07858 | 13/20 | 0.53 |
| ▸ | CTSK | P43235 | 13/20 | 0.53 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14383632 | 0.96 | CTSS (0.59) | CTSSCTSBCTSKCTSL | |
| SCHEMBL6108865 | 0.96 | CTSS (0.59) | CTSSCTSBCTSKCTSL | |
| SCHEMBL6106022 | 0.93 | CTSS (0.53) | CTSSCTSBCTSKCTSL | |
| SCHEMBL6105917 | 0.91 | CTSS (0.56) | CTSSCTSBCTSKCTSL | |
| SCHEMBL6107787 | 0.89 | CTSS (0.56) | CTSSCTSBCTSKCTSL | |
| SCHEMBL6108379 | 0.89 | CTSS (0.63) | CTSSCTSBCTSKCTSL | |
| SCHEMBL6108213 | 0.87 | CTSS (0.52) | CTSSCTSBCTSKCTSL | |
| SCHEMBL6107715 | 0.87 | CTSS (0.58) | CTSSCTSBCTSKCTSL | |
| SCHEMBL6106100 | 0.87 | CTSS (0.57) | CTSSCTSBCTSKCTSL | |
| SCHEMBL6107842 | 0.87 | CTSS (0.57) | CTSSCTSBCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982272-B2 | Compounds useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2006-01-03 | — | — | US | disclosed |