Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.77 |
| ▸ | DRD4 | P21917 | 6/20 | 0.65 |
| ▸ | DRD2 | P14416 | 4/20 | 0.65 |
| ▸ | DRD3 | P35462 | 3/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.65 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.65 |
| ▸ | ACHE | P22303 | 1/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.65 |
| ▸ | HTR2A | P28223 | 1/20 | 0.65 |
| ▸ | HTR2C | P28335 | 1/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.65 |
| ▸ | HTR2B | P41595 | 1/20 | 0.65 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.65 |
| ▸ | HTR3A | P46098 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6109308 | 0.95 | MCHR1 (0.73) | MCHR1DRD4DRD2DRD3CYP3A4 | |
| SCHEMBL6108136 | 0.95 | MCHR1 (0.73) | MCHR1DRD4DRD2DRD3CYP3A4 | |
| SCHEMBL6110799 | 0.94 | MCHR1 (0.71) | MCHR1DRD4DRD2DRD3CYP3A4 | |
| SCHEMBL6109690 | 0.94 | MCHR1 (0.71) | MCHR1DRD4DRD2DRD3CYP3A4 | |
| SCHEMBL6109651 | 0.93 | MCHR1 (0.70) | MCHR1DRD4DRD2DRD3CYP3A4 | |
| SCHEMBL6110279 | 0.92 | MCHR1 (0.69) | MCHR1DRD4DRD2DRD3CYP3A4 | |
| SCHEMBL6109523 | 0.92 | MCHR1 (0.72) | MCHR1DRD4DRD2DRD3CYP3A4 | |
| SCHEMBL6108779 | 0.91 | MCHR1 (0.67) | MCHR1DRD4DRD2DRD3CYP3A4 | |
| SCHEMBL6108797 | 0.90 | MCHR1 (0.69) | MCHR1DRD4DRD2DRD3CYP3A4 | |
| SCHEMBL6108886 | 0.89 | MCHR1 (0.75) | MCHR1DRD4DRD2DRD3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060235035-A1 | Novel methoxybenzamibe compounds for use in mch receptor related disorders | 7TM PHARMA A/S (DK) | 2006-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060235035-A1 | Novel methoxybenzamibe compounds for use in mch receptor related disorders | GPR119, MCHR2, HCRTR2 | MCHR1 5/4885DRD4 237/4885DRD2 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.