SCHEMBL6110397 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	EPHX2	P34913	15/20	0.53

▸	HCRTR1	O43613	1/20	0.49

▸	HCRTR2	O43614	1/20	0.49

▸	MMP2	P08253	2/20	0.44

▸	MMP13	P45452	2/20	0.44

▸	MMP1	P03956	1/20	0.44

▸	MMP3	P08254	1/20	0.44

▸	MMP7	P09237	1/20	0.44

▸	LMNA	P02545	2/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6111069	0.81	EPHX2 (0.52)	EPHX2HCRTR1HCRTR2MMP2MMP13
SCHEMBL6112079	0.81	EPHX2 (0.57)	EPHX2LMNA
SCHEMBL2391747	0.79	EPHX2 (0.43)	EPHX2MMP2MMP13LMNA
SCHEMBL2395689	0.79	EPHX2 (0.43)	EPHX2MMP2MMP13LMNA
SCHEMBL6111072	0.79	EPHX2 (0.48)	EPHX2HCRTR1HCRTR2MMP2MMP13
SCHEMBL15914698	0.79	EPHX2 (0.59)	EPHX2MMP2MMP13
SCHEMBL6120288	0.77	KDM4E (0.43)	EPHX2MMP2MMP13LMNA
SCHEMBL3762883	0.77	KDM4E (0.43)	EPHX2MMP2MMP13LMNA
SCHEMBL2834513	0.76	EPHX2 (0.45)	EPHX2HCRTR1HCRTR2MMP2MMP13
SCHEMBL2840532	0.76	EPHX2 (0.45)	EPHX2HCRTR1HCRTR2MMP2MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2006134481-A1	INHIBITORS OF 11-BETA HYDROXYSTEROID DEHYDROGENASE TYPE 1	PFIZER INC. (US)	2006-12-21	—	—	WO	disclosed