SCHEMBL61104

SCHEMBL61104

C[SiH](C)[Zr](C)(C)(c1cccc2c1Cc1ccccc1-2)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.44
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
HTR7 P34969 1/20 0.36
HTR2B P41595 1/20 0.36
PGR P06401 1/20 0.35
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
MAOA P21397 1/20 0.33
DRD2 P14416 1/20 0.33
DRD4 P21917 1/20 0.33
DRD3 P35462 1/20 0.33
ALDH1A1 P00352 4/20 0.33
KDM4E B2RXH2 2/20 0.33
MAPT P10636 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1130438 0.82 PNMT (0.42) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL5351418 0.82 PNMT (0.42) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL6557465 0.81 PNMT (0.47) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL9223366 0.79 PNMT (0.46) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL7639886 0.79 PNMT (0.46) PNMTNPC1RAB9AHTR7HTR2B
Hydrochloric Acid SCHEMBL6435203 0.79 PNMT (0.46) PNMTNPC1RAB9AHTR7HTR2B
Hydrochloric Acid SCHEMBL3119426 0.78 PNMT (0.45) PNMTNPC1RAB9AHTR7HTR2B
Hydrochloric Acid SCHEMBL9242971 0.78 PNMT (0.45) PNMTNPC1RAB9AHTR7HTR2B
Hydrochloric Acid SCHEMBL7783631 0.78 PNMT (0.45) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL3112715 0.77 PNMT (0.44) PNMTNPC1RAB9AHTR7HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6410665-B1 POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN BASELL POLYOLEFINE GMBH (DE) 2002-06-25 US claimed
EP-3519456-B1 CAPPED MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING AND PROCESS TO PREPARE THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2024-07-03 EP disclosed
EP-3519455-B1 MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING AND PROCESS TO PREPARE THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2024-04-10 EP disclosed
EP-3596138-B1 CATALYST SYSTEM FOR MULTI-BLOCK COPOLYMER FORMATION DOW GLOBAL TECHNOLOGIES LLC (US) 2024-04-03 EP disclosed
US-11897992-B2 Catalyst system for multi-block copolymer formation DOW GLOBAL TECHNOLOGIES LLC (US) 2024-02-13 US disclosed
EP-3596143-B1 CATALYST SYSTEM FOR MULTI-BLOCK COPOLYMER FORMATION DOW GLOBAL TECHNOLOGIES LLC (US) 2023-04-26 EP disclosed
US-11459409-B2 Catalyst system for multi-block copolymer formation DOW GLOBAL TECHNOLOGIES LLC (US) 2022-10-04 US disclosed
US-11359038-B2 Capped multi- or dual-headed compositions useful for chain shuttling and process to prepare the same DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-14 US disclosed
US-11359035-B2 Multi- or dual-headed compositions useful for chain shuttling and process to prepare the same DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-14 US disclosed
EP-2894176-B1 Catalyst composition comprising shuttling agent for regio-irregular multi-block copolymer formation DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-01 EP disclosed
US-20100010161-A1 PRODUCTION OF METATHESIS PRODUCTS BY HIGH MELTING POLYMER SEGMENT INTERCHANGE DOW GLOBAL TECHNOLOGIES INC. (US) 2010-01-14 US disclosed
US-20090264605-A1 TECHNIQUE FOR SELECTING POLYMERIZATION MODIFIERS CORSS REFERENCE STATEMENT DOW GLOBAL TECHNOLOGIES INC. (US) 2009-10-22 US disclosed
US-7553917-B2 Technique for selecting polymerization modifiers cross reference statement DOW GLOBAL TECHNOLOGIES, INC. (US) 2009-06-30 US disclosed
US-20090163667-A1 CATALYTIC OLEFIN BLOCK COPOLYMERS VIA POLYMERIZABLE SHUTTLING AGENT DOW GLOBAL TECHNOLOGIES INC. (US) 2009-06-25 US disclosed
US-20090111944-A1 PSEUDO-BLOCK COPOLYMERS AND PROCESS EMPLOYING CHAIN SHUTTLING AGENT DOW GLOBAL TECHNOLOGIES LLC 2009-04-30 US disclosed
US-20080269412-A1 Catalytic Olefin Block Copolymers with Controlled Block Sequence Distribution DOW GLOBAL TECHNOLOGIES INC. (US) 2008-10-30 US disclosed
US-20080269419-A1 Polymerizing propylene, 4-methyl-1-pentene, or another C4-8 alpha -olefin with a mixture of two metal complex olefin polymerization catalysts, the second catalyst having increased incidence of regio-irregular branching, and a chain shuttling agent such as diethylzinc; heat resistance, melt processability DOW GLOBAL TECHNOLOGIES LLC 2008-10-30 US disclosed
US-20080262175-A1 Catalyst Composition Comprising Shuttling Agent for Regio-Irregular Multi-Block Copolymer Formation DOW GLOBAL TECHNOLOGIES LLC 2008-10-23 US disclosed
US-20070219327-A1 Technique for Selecting Polymerization Modifiers Cross Reference Statement DOW GLOBAL TECHNOLOGIES INC. 2007-09-20 US disclosed
US-6410665-B1 POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN BASELL POLYOLEFINE GMBH (DE) 2002-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090264605-A1 TECHNIQUE FOR SELECTING POLYMERIZATION MODIFIERS CORSS REFERENCE STATEMENT NOTUM, COASY, WASF2 PNMT 268/4885NPC1 3425/4885RAB9A 4047/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.