Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 17/20 | 0.66 |
| ▸ | MCHR2 | Q969V1 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6111247 | 0.95 | MCHR1 (0.71) | MCHR1 | |
| SCHEMBL6108353 | 0.90 | MCHR1 (0.69) | MCHR1MCHR2 | |
| SCHEMBL6110642 | 0.85 | MCHR1 (0.62) | MCHR1MCHR2BACE1BACE2 | |
| SCHEMBL6109142 | 0.84 | MCHR1 (0.70) | MCHR1BACE1BACE2 | |
| SCHEMBL6109370 | 0.83 | MCHR1 (0.81) | MCHR1 | |
| SCHEMBL6111240 | 0.83 | MCHR1 (0.64) | MCHR1MCHR2 | |
| SCHEMBL6108709 | 0.81 | MCHR1 (0.76) | MCHR1MCHR2BACE1BACE2 | |
| SCHEMBL6108371 | 0.81 | MCHR1 (0.69) | MCHR1MCHR2 | |
| SCHEMBL6109784 | 0.81 | MCHR1 (0.84) | MCHR1 | |
| SCHEMBL6108263 | 0.81 | CYP1A2 (0.60) | MCHR1MCHR2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060235035-A1 | Novel methoxybenzamibe compounds for use in mch receptor related disorders | 7TM PHARMA A/S (DK) | 2006-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060235035-A1 | Novel methoxybenzamibe compounds for use in mch receptor related disorders | GPR119, MCHR2, HCRTR2 | MCHR1 5/4885MCHR2 2/4885TP53 4848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.