Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.81 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.61 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6110742 | 1.00 | ADRB2 (0.81) | ADRB2ADRB1CHRM3 | |
| SCHEMBL6110875 | 0.91 | ADRB2 (0.93) | ADRB2ADRB1CHRM3 | |
| SCHEMBL6110868 | 0.91 | ADRB2 (0.93) | ADRB2ADRB1CHRM3 | |
| SCHEMBL6111168 | 0.90 | ADRB2 (0.81) | ADRB2ADRB1CHRM3 | |
| SCHEMBL6111159 | 0.90 | ADRB2 (0.81) | ADRB2ADRB1CHRM3 | |
| SCHEMBL4384664 | 0.89 | ADRB2 (1.00) | ADRB2ADRB1CHRM3 | |
| SCHEMBL4384659 | 0.89 | ADRB2 (1.00) | ADRB2ADRB1CHRM3 | |
| SCHEMBL6110609 | 0.87 | ADRB2 (0.82) | ADRB2ADRB1CHRM3 | |
| SCHEMBL6110617 | 0.87 | ADRB2 (0.82) | ADRB2ADRB1CHRM3 | |
| SCHEMBL6110149 | 0.86 | ADRB2 (0.80) | ADRB2ADRB1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006051373-A1 | COMPOUNDS FOR THE TREATMENT OF DISEASES | PFIZER LIMITED (GB) | 2006-05-18 | — | — | WO | claimed |
| WO-2006051373-A1 | COMPOUNDS FOR THE TREATMENT OF DISEASES | PFIZER LIMITED (GB) | 2006-05-18 | — | — | WO | disclosed |