Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | BCHE | P06276 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3719676 | 0.92 | BCHE (0.50) | ALDH1A1BCHELMNAPOLBTSHR | |
| SCHEMBL3375350 | 0.90 | BCHE (0.44) | ALDH1A1BCHELMNAPOLBMAPT | |
| SCHEMBL6110404 | 0.82 | P2RX4 (0.50) | ALDH1A1POLBHPGDTSHRSMN1; SMN2 | |
| SCHEMBL27711169 | 0.81 | P2RX4 (0.42) | ALDH1A1BCHELMNAMAPTHPGD | |
| SCHEMBL5670700 | 0.77 | BCHE (0.46) | BCHEPOLBNOTUMKMT2A | |
| SCHEMBL6110762 | 0.77 | P2RX4 (0.46) | ALDH1A1BCHELMNAHPGDTSHR | |
| SCHEMBL6980620 | 0.74 | POLB (0.54) | ALDH1A1BCHELMNAPOLBTSHR | |
| SCHEMBL1629578 | 0.74 | NPC1 (0.39) | ALDH1A1POLBMAPTHPGDTSHR | |
| SCHEMBL10841005 | 0.74 | NPC1 (0.39) | ALDH1A1MAPTHPGDTSHRSMN1; SMN2 | |
| SCHEMBL3266678 | 0.72 | MEN1 (0.41) | ALDH1A1BCHELMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1458840-A | Pharmaceutical composition of cholesteryl ester transfer protein inhibitor | PFIZER PROD INC (US) | 2003-11-26 | — | — | CN | claimed |
| WO-2006033004-A1 | QUINOLINE COMPOUNDS AS CETP INHIBITORS | PFIZER PRODUCTS INC. (US) | 2006-03-30 | — | — | WO | disclosed |
| CN-1625397-A | Controlled release pharmaceutical dosage forms of a cholesteryl ester transfer protein inhibitor | PFIZER PROD INC (US) | 2005-06-08 | — | — | CN | disclosed |
| CN-1545421-A | Pharmaceutical composition comprising a low-solubility and/or acid-sensitive drug and a neutralized acidic polymer | �Ʒ� | 2004-11-10 | — | — | CN | disclosed |
| EP-1469831-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING A SOLID AMORPHOUS DISPERSION OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS | Pfizer Products Inc. (US) | 2004-10-27 | — | — | EP | disclosed |
| EP-1401399-A2 | PHARMACEUTICAL COMPOSITIONS CONTAINING POLYMER AND DRUG ASSEMBLIES | Pfizer Products Inc. (US) | 2004-03-31 | — | — | EP | disclosed |
| CN-1458840-A | Pharmaceutical composition of cholesteryl ester transfer protein inhibitor | PFIZER PROD INC (US) | 2003-11-26 | — | — | CN | disclosed |
| WO-2003063832-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING A SOLID AMORPHOUS DISPERSION OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS | PFIZER PRODUCTS INC. (US) | 2003-08-07 | — | — | WO | disclosed |
| WO-2003000226-A2 | PHARMACEUTICAL COMPOSITIONS CONTAINING POLYMER AND DRUG ASSEMBLIES | PFIZER PRODUCTS INC. (US) | 2003-01-03 | — | — | WO | disclosed |