Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6110995 | 0.92 | ALDH1A1 (0.41) | BCHETSHRL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL3375350 | 0.88 | BCHE (0.44) | BCHETSHRKMT2AMEN1TP53 | |
| SCHEMBL6110404 | 0.80 | P2RX4 (0.50) | TSHRL3MBTL1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27711169 | 0.79 | P2RX4 (0.42) | BCHETSHRL3MBTL1KMT2AMEN1 | |
| SCHEMBL6110762 | 0.75 | P2RX4 (0.46) | BCHETSHRL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL5670700 | 0.75 | BCHE (0.46) | BCHEKMT2AMEN1MAPK1POLB | |
| SCHEMBL5797625 | 0.73 | RAB9A (0.63) | BCHETSHRL3MBTL1KMT2AMEN1 | |
| SCHEMBL6980620 | 0.72 | POLB (0.54) | BCHETSHRL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL27569955 | 0.72 | BCHE (0.58) | BCHETSHRTDP1L3MBTL1KMT2A | |
| SCHEMBL1629578 | 0.72 | NPC1 (0.39) | TSHRTDP1L3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097091-A1 | METHODS OF ADMINISTERING (4AR, 1OAR)-I-N-PROPYL-I, 2,3,4A7 S1IO7 IOA-OCTAHYDROBENZO [G] QUINOLINE-6,7-DIOL AND RELATED COMPOUNDS ACROSS THE ORAL MUCOSA, THE NASAL MUCOSA OR THE SKIN AND PHARMACEUTICAL COMPOSITIONS THEREOF | H. LUNDBECK A/S (DK) | 2010-09-02 | — | — | WO | disclosed |