SCHEMBL6111748

SCHEMBL6111748

COc1cc(NC(=O)Nc2cccc(Cl)c2)ccc1C(=O)NCCN(C)C

nearest known ligand 0.68

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MCHR1 Q99705 19/20 0.68
▸ MEN1 O00255 1/20 0.55
▸ NPC1 O15118 1/20 0.55
▸ RAB9A P51151 1/20 0.55
▸ KMT2A Q03164 1/20 0.55
▸ ATM Q13315 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6109329 0.90 MCHR1 (0.85) MCHR1
SCHEMBL6110991 0.89 MCHR1 (0.79) MCHR1
SCHEMBL6112412 0.85 MCHR1 (0.73) MCHR1
SCHEMBL6109084 0.84 MCHR1 (0.85) MCHR1
SCHEMBL6109600 0.82 MCHR1 (0.82) MCHR1
SCHEMBL6108757 0.81 MCHR1 (1.00) MCHR1
SCHEMBL6109370 0.81 MCHR1 (0.81) MCHR1
SCHEMBL6108330 0.81 MCHR1 (0.74) MCHR1
SCHEMBL6108567 0.80 MCHR1 (0.82) MCHR1
SCHEMBL6109794 0.79 MCHR1 (0.78) MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060235035-A1 Novel methoxybenzamibe compounds for use in mch receptor related disorders 7TM PHARMA A/S (DK) 2006-10-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060235035-A1 Novel methoxybenzamibe compounds for use in mch receptor related disorders GPR119, MCHR2, HCRTR2 MCHR1 5/4885MEN1 3602/4885NPC1 2225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback