Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 18/20 | 0.81 |
| ▸ | CYP2C9 | P11712 | 14/20 | 0.81 |
| ▸ | CYP2C19 | P33261 | 14/20 | 0.81 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.81 |
| ▸ | CYP2D6 | P10635 | 9/20 | 0.81 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.81 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.54 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.54 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.54 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6112662 | 1.00 | CYP3A4 (0.81) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL7801327 | 0.94 | CYP3A4 (0.88) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL7801331 | 0.94 | CYP3A4 (0.88) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL12895673 | 0.91 | CYP3A4 (0.83) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2D6 | |
| Albaconazole SCHEMBL23900808 | 0.90 | CYP3A4 (1.00) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL7813492 | 0.90 | CYP3A4 (0.81) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2D6 | |
| Albaconazole SCHEMBL1262831 | 0.90 | CYP3A4 (1.00) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL7813489 | 0.90 | CYP3A4 (0.81) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2D6 | |
| Albaconazole SCHEMBL1262830 | 0.90 | CYP3A4 (1.00) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL6112711 | 0.90 | CYP3A4 (0.81) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10251885-B2 | Azole antifungal compositions | ALLERGAN PHARMACEUTICALS INTERNATIONAL LIMITED (IE) | 2019-04-09 | — | — | US | claimed |
| EP-2434892-B1 | AZOLE ANTIFUNGAL COMPOSITIONS | PALAU PHARMA SA (ES) | 2015-08-19 | — | — | EP | claimed |
| US-20120128612-A1 | AZOLE ANTIFUNGAL COMPOSITIONS | PALAU PHARMA, S.A. (ES) | 2012-05-24 | — | — | US | claimed |
| EP-0783501-B9 | PYRIMIDONE DERIVATIVES WITH ANTIFUNGAL ACTIVITY | URIACH & CIA SA J (ES) | 2001-07-25 | — | — | EP | claimed |
| EP-0783501-B1 | PYRIMIDONE DERIVATIVES WITH ANTIFUNGAL ACTIVITY | URIACH & CIA SA J (ES) | 2001-01-10 | — | — | EP | claimed |
| WO-1997005130-A1 | NEW PYRIMIDONE DERIVATIVES WITH ANTIFUNGAL ACTIVITY | J. URIACH & CIA. S.A. (ES) | 1997-02-13 | — | — | WO | claimed |
| US-10251885-B2 | Azole antifungal compositions | ALLERGAN PHARMACEUTICALS INTERNATIONAL LIMITED (IE) | 2019-04-09 | — | — | US | disclosed |
| EP-2434892-B1 | AZOLE ANTIFUNGAL COMPOSITIONS | PALAU PHARMA SA (ES) | 2015-08-19 | — | — | EP | disclosed |
| US-20120128612-A1 | AZOLE ANTIFUNGAL COMPOSITIONS | PALAU PHARMA, S.A. (ES) | 2012-05-24 | — | — | US | disclosed |
| EP-0783501-B9 | PYRIMIDONE DERIVATIVES WITH ANTIFUNGAL ACTIVITY | URIACH & CIA SA J (ES) | 2001-07-25 | — | — | EP | disclosed |
| EP-0783501-B1 | PYRIMIDONE DERIVATIVES WITH ANTIFUNGAL ACTIVITY | URIACH & CIA SA J (ES) | 2001-01-10 | — | — | EP | disclosed |
| WO-1997005130-A1 | NEW PYRIMIDONE DERIVATIVES WITH ANTIFUNGAL ACTIVITY | J. URIACH & CIA. S.A. (ES) | 1997-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120128612-A1 | AZOLE ANTIFUNGAL COMPOSITIONS | DPM1, POLR1C, PIK3C3 | CYP3A4 877/4885CYP2C9 1052/4885CYP2C19 465/4885 |
| US-10251885-B2 | Azole antifungal compositions | DPM1, POLR1C, PIK3C3 | CYP3A4 877/4885CYP2C9 1052/4885CYP2C19 465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.