⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166924 | 0.88 | — | — | |
| SCHEMBL9609723 | 0.78 | CYP1A2 (0.30) | — | |
| SCHEMBL7063450 | 0.78 | CYP1A2 (0.30) | — | |
| SCHEMBL117583 | 0.75 | — | — | |
| SCHEMBL7090715 | 0.74 | — | — | |
| SCHEMBL13922640 | 0.73 | — | — | |
| SCHEMBL163893 | 0.73 | — | — | |
| SCHEMBL23061486 | 0.72 | PTGS1 (0.32) | — | |
| SCHEMBL20478203 | 0.72 | PTGS1 (0.32) | — | |
| SCHEMBL15659548 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2790829-B1 | NON-PRECIOUS METAL-BASED HYDROSILYLATION CATALYSTS | MOMENTIVE PERFORMANCE MAT INC (US) | 2022-12-07 | — | — | EP | disclosed |
| US-11052383-B2 | Non-precious metal-based hyrdosilylation catalysts exhibiting improved selectivity | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2021-07-06 | — | — | US | disclosed |
| US-20180015449-A1 | Non-precious Metal-based Hyrdosilylation Catalysts Exhibiting Improved Selectivity | MOMENTIVE PERFORMANCE MATERIALS INC. | 2018-01-18 | — | — | US | disclosed |
| US-9782763-B2 | Non-precious metal-based hyrdosilylation catalysts exhibiting improved selectivity | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2017-10-10 | — | — | US | disclosed |
| EP-2643330-B1 | METAL-CATALYZED MONO-HYDROSILYLATION OF POLYUNSATURATED COMPOUNDS | MOMENTIVE PERFORMANCE MAT INC (US) | 2017-01-04 | — | — | EP | disclosed |
| EP-2643329-B1 | IN-SITU ACTIVATION OF METAL COMPLEXES USED AS HYDROSILYLATION CATALYSTS | MOMENTIVE PERFORMANCE MAT INC (US) | 2016-07-27 | — | — | EP | disclosed |
| US-8895770-B2 | Selective non-precious metal-catalyzed mono-hydrosilylation polyunsaturated compounds | CORNELL UNIVERSITY (US) | 2014-11-25 | — | — | US | disclosed |
| EP-2790829-A1 | NON- PRECIOUS METAL -BASED HYDROSILYLATION CATALYSTS | Momentive Performance Materials Inc. (US) | 2014-10-22 | — | — | EP | disclosed |
| US-20130158281-A1 | Non-precious Metal-based Hyrdosilylation Catalysts Exhibiting Improved Selectivity | PRINCETON UNIVERSITY (US) | 2013-06-20 | — | — | US | disclosed |
| WO-2013090548-A1 | NON- PRECIOUS METAL -BASED HYDROSILYLATION CATALYSTS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2013-06-20 | — | — | WO | disclosed |
| US-20120130105-A1 | SELECTIVE NON-PRECIOUS METAL-CATALYZED MONO-HYDROSILYLATION OF POLYUNSATURATED COMPOUNDS | CORNELL UNIVERSITY (US) | 2012-05-24 | — | — | US | disclosed |