⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7063450 | 0.86 | CYP1A2 (0.30) | — | |
| SCHEMBL9609723 | 0.86 | CYP1A2 (0.30) | — | |
| SCHEMBL23521394 | 0.80 | CYP1A2 (0.45) | — | |
| SCHEMBL6112855 | 0.80 | CYP1A2 (0.45) | — | |
| SCHEMBL117583 | 0.78 | — | — | |
| SCHEMBL4925105 | 0.77 | — | — | |
| SCHEMBL3909897 | 0.77 | GNAO1 (0.36) | — | |
| SCHEMBL18458681 | 0.77 | SHBG (0.32) | — | |
| SCHEMBL13922640 | 0.77 | — | — | |
| SCHEMBL114741 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991698-B1 | SILICONE OLIGOMERS AND CURABLE COMPOSITIONS CONTAINING SAME | MOMENTIVE PERFORMANCE MAT INC (US) | 2012-10-24 | — | — | EP | disclosed |
| WO-2003000775-A9 | REACTIVE DILUENT IN MOISTURE CURABLE SYSTEM | CROMPTON CORP (US) | 2003-12-31 | — | — | WO | disclosed |
| US-6602964-B2 | Silicone oligomers as reactive diluents for curable silylated polyurethanes and/or silylated polyethers; use as high modulus sealants or low viscosity coatings, adhesives and sealants | CROMPTON CORPORATION | 2003-08-05 | — | — | US | disclosed |
| US-6515043-B2 | Surface treatment of filler | CROMPTON CORPORATION | 2003-02-04 | — | — | US | disclosed |
| US-20020115811-A1 | Reactive diluent in moisture curable system | CROMPTON CORPORATION | 2002-08-22 | — | — | US | disclosed |
| US-6395856-B1 | CURABLE POLYSILOXANES FOR PROTECTIVE COATINGS FOR WIRES | CROMPTON CORPORATION | 2002-05-28 | — | — | US | disclosed |
| US-6323277-B1 | USFUL AS COUPLING AGENTS IN CURABLE FILLED ORGANIC POLYMERS USED FOR WIRE AND CABLE INSULATION | WITCO CORPORATION | 2001-11-27 | — | — | US | disclosed |
| US-20010021761-A1 | Silicone oligomers with heigher alkoxy groups | MOMENTIVE PERFORMANCE MATERIALS INC. | 2001-09-13 | — | — | US | disclosed |
| US-6207783-B1 | UNDERGROUND INSULATION | CROMPTON CORPORATION | 2001-03-27 | — | — | US | disclosed |