Butyric Acid

Butyric Acid

SCHEMBL611749

CCCC(=O)O.O=C(O)CO

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.81
HDAC3 O15379 1/20 0.81
HDAC1 Q13547 1/20 0.81
HDAC2 Q92769 1/20 0.81
HDAC8 Q9BY41 1/20 0.81
AKR1B1 P15121 1/20 0.52
GPR84 Q9NQS5 7/20 0.50
PPARG P37231 7/20 0.50
PPARD Q03181 7/20 0.50
PPARA Q07869 7/20 0.50
HDAC11 Q96DB2 5/20 0.50
TSHR P16473 4/20 0.50
PTPN1 P18031 3/20 0.50
ALDH1A1 P00352 2/20 0.50
TLR2 O60603 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
FABP4 P15090 2/20 0.50
KMT2A Q03164 2/20 0.50
SLC22A6 Q4U2R8 1/20 0.50
SLC22A8 Q8TCC7 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butyric Acid SCHEMBL15610536 0.90
Butyric Acid SCHEMBL1690482 0.90
Butyric Acid SCHEMBL27614175 0.90
Butyric Acid SCHEMBL5571639 0.90 FFAR3 (0.87) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL49424 0.90
Butyric Acid SCHEMBL991717 0.90 FFAR3 (1.00) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL1332215 0.90
Butyric Acid SCHEMBL8458708 0.90 FFAR3 (1.00) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL8457839 0.90 FFAR3 (1.00) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL20678495 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115745946-B Low-temperature preparation method of glycolide and lactide 中国科学院长春应用化学研究所 2024-03-26 CN claimed
CN-115650948-B Preparation method of glycolide-lactide 中国科学院长春应用化学研究所 2023-12-19 CN claimed
CN-115745946-A Low-temperature preparation method of glycolide-lactide 中国科学院长春应用化学研究所 2023-03-07 CN claimed
CN-115650948-A Preparation method of glycolide-lactide 中国科学院长春应用化学研究所 2023-01-31 CN claimed
US-12024512-B2 Cocrystal TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-07-02 US disclosed
CN-115745946-B Low-temperature preparation method of glycolide and lactide 中国科学院长春应用化学研究所 2024-03-26 CN disclosed
WO-2023249105-A1 THERAPEUTIC AGENT OR PREVENTIVE AGENT FOR DRUG-INDUCED MYOCARDIAL DISORDERS 東レ株式会社 2023-12-28 WO disclosed
WO-2023249107-A1 THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR PERIPHERAL NERVE DISORDER 東レ株式会社 2023-12-28 WO disclosed
WO-2023249106-A1 THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR AMYOTROPHIC LATERAL SCLEROSIS 東レ株式会社 2023-12-28 WO disclosed
CN-115650948-B Preparation method of glycolide-lactide 中国科学院长春应用化学研究所 2023-12-19 CN disclosed
CN-115745946-A Low-temperature preparation method of glycolide-lactide 中国科学院长春应用化学研究所 2023-03-07 CN disclosed
CN-115650948-A Preparation method of glycolide-lactide 中国科学院长春应用化学研究所 2023-01-31 CN disclosed
EP-1484320-A1 JNK INHIBITOR Takeda Chemical Industries, Ltd. (JP) 2004-12-08 EP disclosed
EP-1471064-A1 COUMARIN DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF Takeda Chemical Industries, Ltd. (JP) 2004-10-27 EP disclosed
US-20040038986-A1 Carbamate derivatives, process for producing the same and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-02-26 US disclosed
US-20030187023-A1 Sulfone derivatives, process for their production and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2003-10-02 US disclosed
EP-1340753-A1 CARBAMATE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF Takeda Chemical Industries, Ltd. (JP) 2003-09-03 EP disclosed
US-20030139616-A1 Method of searching for arteriosclerosis inhibitors and shrinkers TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2003-07-24 US disclosed
EP-1302462-A1 SULFONE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF Takeda Chemical Industries, Ltd. (JP) 2003-04-16 EP disclosed
EP-1277760-A1 METHOD OF SEARCHING FOR ARTERIOSCLEROSIS INHIBITORS AND SHRINKERS Takeda Chemical Industries, Ltd. (JP) 2003-01-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040038986-A1 Carbamate derivatives, process for producing the same and use thereof CFH, F11, F2 FFAR3 1402/4885HDAC3 29/4885HDAC1 77/4885
US-20030187023-A1 Sulfone derivatives, process for their production and use thereof SULT1E1, RRS1, SHH FFAR3 1514/4885HDAC3 1828/4885HDAC1 1405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.