Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.40 |
| ▸ | NT5E | P21589 | 6/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GLI1 | P08151 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 2/20 | 0.39 |
| ▸ | PRKCG | P05129 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6119088 | 0.89 | RORC (0.50) | NT5EPTPN1GPBAR1RORCUSP2 | |
| SCHEMBL6112771 | 0.86 | SLC10A1 (0.40) | SLC10A1NT5EPTPN1GPBAR1RORC | |
| SCHEMBL6119240 | 0.82 | SLC10A1 (0.40) | SLC10A1NT5EPTPN1GPBAR1RORC | |
| SCHEMBL3797717 | 0.80 | NT5E (0.61) | SLC10A1NT5EPTPN1GPBAR1RORC | |
| SCHEMBL3797721 | 0.80 | NT5E (0.61) | SLC10A1NT5EPTPN1GPBAR1RORC | |
| SCHEMBL6112792 | 0.80 | PTPN1 (0.51) | SLC10A1NT5EPTPN1GPBAR1RORC | |
| SCHEMBL6112790 | 0.80 | PTPN1 (0.51) | SLC10A1NT5EPTPN1GPBAR1RORC | |
| SCHEMBL3791454 | 0.79 | SLC10A1 (0.57) | SLC10A1NT5EPTPN1USP2LMNA | |
| SCHEMBL3791455 | 0.79 | SLC10A1 (0.57) | SLC10A1NT5EPTPN1USP2LMNA | |
| SCHEMBL3791751 | 0.76 | RORC (0.52) | NT5EPTPN1GPBAR1RORCUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8969395-B2 | Triterpenoid derivatives useful as antiproliferative agents | UNIVERSIDADE DE COIMBRA (PT) | 2015-03-03 | — | — | US | disclosed |
| US-20120129901-A1 | TRITERPENOID DERIVATIVES USEFUL AS ANTIPROLIFERATIVE AGENTS | UNIVERSIDADE DE COIMBRA (PT) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129901-A1 | TRITERPENOID DERIVATIVES USEFUL AS ANTIPROLIFERATIVE AGENTS | ALPI, LSS, CYP46A1 | SLC10A1 43/4885NT5E 4541/4885PTPN1 3105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.