Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6119223 | 0.88 | KDM4E (0.46) | CYP4F2CYP4A11GAAHPGDLMNA | |
| SCHEMBL6120486 | 0.81 | KDM4E (0.41) | CYP4F2CYP4A11GAAHPGDTSHR | |
| SCHEMBL28406215 | 0.80 | ABL1 (0.46) | GAAHPGDLMNAMAPTALDH1A1 | |
| SCHEMBL844331 | 0.79 | CYP4F2 (0.72) | CYP4F2CYP4A11GAAHPGDLMNA | |
| SCHEMBL30750476 | 0.79 | CYP4F2 (0.72) | CYP4F2CYP4A11GAAHPGDLMNA | |
| SCHEMBL1830479 | 0.79 | CYP4F2 (0.55) | CYP4F2CYP4A11GAAHPGDLMNA | |
| SCHEMBL6118711 | 0.78 | GAA (0.42) | GAAHPGDLMNAMAPTALDH1A1 | |
| SCHEMBL26596781 | 0.78 | KDM4E (0.46) | CYP4F2CYP4A11GAAHPGDLMNA | |
| SCHEMBL6120235 | 0.77 | NOTUM (0.46) | CYP4F2CYP4A11GAAHPGDLMNA | |
| SCHEMBL3722864 | 0.77 | NQO2 (0.51) | GAAHPGDLMNATSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012067663-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-05-24 | — | — | WO | disclosed |