Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6119223 | 0.88 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL6119323 | 0.81 | CYP4F2 (0.47) | KDM4EALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL6120235 | 0.80 | NOTUM (0.46) | KDM4EALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL28406632 | 0.80 | CES2 (0.42) | KDM4EALDH1A1GAAMAPTTSHR | |
| SCHEMBL21957016 | 0.80 | CYP4F2 (0.40) | KDM4EGAAMAPTHPGDTSHR | |
| SCHEMBL6119252 | 0.80 | SOS1 (0.42) | KDM4EHSD17B10GAAMAPTTSHR | |
| SCHEMBL30842613 | 0.79 | ALDH1A1 (0.49) | KDM4EALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL489064 | 0.79 | ALDH1A1 (0.45) | KDM4EALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL2060890 | 0.79 | ALDH1A1 (0.49) | KDM4EALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL24526306 | 0.79 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012067663-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-05-24 | — | — | WO | disclosed |