Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STIM1 | Q13586 | 1/20 | 0.49 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 10/20 | 0.48 |
| ▸ | CDK9 | P50750 | 10/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6118493 | 0.89 | CCNT1 (0.48) | STIM1ORAI1CCNT1CDK9CLK4 | |
| SCHEMBL6118228 | 0.86 | CDK9 (0.46) | STIM1ORAI1CCNT1CDK9CLK4 | |
| SCHEMBL6118660 | 0.84 | CCNT1 (0.58) | STIM1ORAI1CCNT1CDK9CLK4 | |
| SCHEMBL8797737 | 0.80 | CCNT1 (0.70) | CCNT1CDK9 | |
| SCHEMBL6122817 | 0.80 | CCNT1 (0.73) | STIM1ORAI1CCNT1CDK9 | |
| SCHEMBL1192389 | 0.79 | CCNT1 (0.58) | CCNT1 | |
| SCHEMBL6118582 | 0.79 | CCNT1 (0.60) | CCNT1 | |
| SCHEMBL6118589 | 0.79 | CCNT1 (0.60) | CCNT1 | |
| SCHEMBL8789416 | 0.77 | CCNT1 (0.65) | CCNT1CDK9 | |
| SCHEMBL30859468 | 0.76 | CCNT1 (0.80) | CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012066065-A1 | PHENYL-HETEROARYL AMINE COMPOUNDS AND THEIR USES | NOVARTIS AG (CH) | 2012-05-24 | — | — | WO | disclosed |