Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 16/20 | 0.69 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 12/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12187984 | 0.79 | PTGS1 (0.49) | PTGS1SLC22A12PTGS2 | |
| SCHEMBL28444470 | 0.77 | SLC22A12 (1.00) | PTGS1SLC22A12PTGS2CYP17A1 | |
| SCHEMBL14960632 | 0.77 | PTGS1 (0.67) | PTGS1PTGS2 | |
| SCHEMBL1934993 | 0.76 | PTGS1 (0.54) | PTGS1SLC22A12PTGS2 | |
| SCHEMBL4483021 | 0.76 | AOC1 (0.48) | PTGS1SLC22A12PTGS2CA12CA1 | |
| SCHEMBL19788231 | 0.75 | PTGS1 (0.55) | PTGS1PTGS2 | |
| SCHEMBL5806458 | 0.75 | PTGS1 (0.55) | PTGS1PTGS2 | |
| SCHEMBL526941 | 0.74 | CYP17A1 (0.70) | PTGS1SLC22A12PTGS2CYP17A1 | |
| SCHEMBL14995307 | 0.74 | CA12 (0.49) | PTGS1SLC22A12PTGS2CA12CA1 | |
| SCHEMBL4860020 | 0.74 | PTGS1 (0.63) | PTGS1SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012067664-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-05-24 | — | — | WO | disclosed |