Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6122370 | 0.97 | NAMPT (0.46) | EPHX2RAB9ANPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL6123113 | 0.94 | SMN1; SMN2 (0.50) | RAB9ANPC1SMN1; SMN2NAMPTKMT2A | |
| SCHEMBL6121468 | 0.82 | RORC (0.46) | RAB9ASMN1; SMN2 | |
| SCHEMBL4155148 | 0.79 | EPHX1 (0.44) | SMN1; SMN2HPGDKMT2AMEN1EPHX1 | |
| SCHEMBL6121438 | 0.79 | NAMPT (0.53) | RAB9ANPC1NAMPT | |
| Hydrochloric Acid SCHEMBL15569626 | 0.78 | TSHR (0.48) | RAB9ASMN1; SMN2HPGDKMT2AMEN1 | |
| SCHEMBL6122090 | 0.78 | NAMPT (0.56) | NAMPT | |
| SCHEMBL6122532 | 0.77 | NAMPT (0.59) | NAMPT | |
| SCHEMBL4164018 | 0.76 | SMYD3 (0.43) | RAB9ANPC1SMN1; SMN2CYP1A2HPGD | |
| SCHEMBL6120508 | 0.76 | NAMPT (0.57) | RAB9ANPC1NAMPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2640698-A1 | NAMPT AND ROCK INHIBITORS | AbbVie Inc. (US) | 2013-09-25 | — | — | EP | disclosed |
| WO-2012067965-A1 | NAMPT AND ROCK INHIBITORS | ABBOTT LABORATORIES (US) | 2012-05-24 | — | — | WO | disclosed |