Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | THRB | P10828 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13646750 | 0.87 | MAPT (0.66) | MAPTALDH1A1KDM4ETDP1CYP2C19 | |
| SCHEMBL6120557 | 0.86 | MAPT (0.51) | MAPTALDH1A1KDM4ETDP1CYP2C19 | |
| Bromide SCHEMBL6120521 | 0.85 | MAPT (0.64) | MAPTALDH1A1KDM4ETDP1CYP2C19 | |
| SCHEMBL14403381 | 0.83 | MAPT (0.75) | MAPTALDH1A1KDM4ETDP1CYP2C19 | |
| Iodide SCHEMBL2987038 | 0.82 | MAPT (0.78) | MAPTALDH1A1KDM4ETDP1CYP2C19 | |
| SCHEMBL15242436 | 0.81 | MAPT (0.71) | MAPTALDH1A1KDM4ETDP1CYP2C19 | |
| SCHEMBL5675161 | 0.78 | HPGD (0.66) | MAPTALDH1A1KDM4ETDP1CYP2C19 | |
| SCHEMBL7251971 | 0.78 | MAPT (0.73) | MAPTALDH1A1KDM4ETDP1CYP2C19 | |
| Water SCHEMBL1046380 | 0.77 | HPGD (0.64) | MAPTALDH1A1KDM4ETDP1CYP2C19 | |
| SCHEMBL8032355 | 0.74 | MAPT (0.97) | MAPTALDH1A1KDM4ETDP1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2640427-A1 | USE OF CYANINE DYES FOR THE DETECTION OF TAU FOR DIAGNOSIS OF EARLY-STAGE TAUOPATHIES | GE Healthcare UK Limited (GB) | 2013-09-25 | — | — | EP | disclosed |
| WO-2012068072-A1 | USE OF CYANINE DYES FOR THE DETECTION OF TAU FOR DIAGNOSIS OF EARLY-STAGE TAUOPATHIES | GE HEALTHCARE LIMITED (GB) | 2012-05-24 | — | — | WO | disclosed |