Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.97 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.97 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.97 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.97 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL4015595 | 0.98 | MAPT (1.00) | MAPTALDH1A1KDM4ETDP1GAA | |
| SCHEMBL13652077 | 0.86 | MAPT (0.73) | MAPTALDH1A1KDM4ETDP1GAA | |
| Iodide SCHEMBL31063745 | 0.84 | MAPT (0.76) | MAPTALDH1A1KDM4ETDP1GAA | |
| Iodide SCHEMBL29039127 | 0.84 | MAPT (0.76) | MAPTALDH1A1KDM4ETDP1GAA | |
| SCHEMBL13652085 | 0.81 | MAPT (0.67) | MAPTALDH1A1KDM4ETDP1GAA | |
| SCHEMBL14403381 | 0.78 | MAPT (0.75) | MAPTALDH1A1KDM4ETDP1GAA | |
| SCHEMBL14434817 | 0.77 | MAPT (0.61) | MAPTALDH1A1KDM4ETDP1GAA | |
| Iodide SCHEMBL2987038 | 0.77 | MAPT (0.78) | MAPTALDH1A1KDM4ETDP1GAA | |
| SCHEMBL13646750 | 0.76 | MAPT (0.66) | MAPTALDH1A1KDM4ETDP1GAA | |
| Iodide SCHEMBL11599406 | 0.76 | MAPT (0.62) | MAPTALDH1A1KDM4ETDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4874866-A | AROMATIC TELLURIUM-NITROGEN COMPOUNDS; DYES | EASTMAN KODAK COMPANY (US) | 1989-10-17 | — | — | US | claimed |
| WO-2009085226-A2 | INHIBITORS OF CDC2-LIKE KINASES (CLKS) AND METHODS OF USE THEREOF | SIRTRIS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |