Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 4/20 | 0.34 |
| ▸ | SLC34A1 | Q06495 | 8/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6120931 | 0.94 | BRAF (0.35) | BRAFSLC34A1LMNACA12CA1 | |
| SCHEMBL6120407 | 0.94 | BRAF (0.33) | BRAF | |
| SCHEMBL6120580 | 0.91 | SLC34A1 (0.32) | BRAFSLC34A1CHRNA7ALDH1A1 | |
| SCHEMBL6121529 | 0.90 | BRAF (0.37) | BRAF | |
| SCHEMBL6121002 | 0.90 | BRAF (0.34) | BRAF | |
| SCHEMBL6121823 | 0.89 | CYP3A4 (0.36) | BRAF | |
| SCHEMBL6120439 | 0.89 | PTGES2 (0.35) | BRAF | |
| SCHEMBL6120362 | 0.89 | MAPK8 (0.39) | BRAFSLC34A1KDM4EALDH1A1GAA | |
| SCHEMBL6121578 | 0.85 | BRAF (0.33) | BRAF | |
| SCHEMBL6120643 | 0.84 | BRAF (0.34) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012067664-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-05-24 | — | — | WO | disclosed |