Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16916365 | 1.00 | KDM4E (0.46) | KDM4EGAACYP11B2POLBCASP3 | |
| SCHEMBL676894 | 0.97 | KDM4E (0.43) | KDM4EGAACYP11B2POLBCASP3 | |
| Ammonia Solution, Strong SCHEMBL28326987 | 0.95 | KDM4E (0.41) | KDM4EGAACYP11B2POLBCASP3 | |
| SCHEMBL1444138 | 0.92 | KDM4E (0.38) | KDM4EGAACYP11B2POLBCASP3 | |
| SCHEMBL935722 | 0.86 | — | — | |
| Carbamic Acid SCHEMBL9705391 | 0.85 | KDM4E (0.45) | KDM4EGAACYP11B2POLBCASP3 | |
| Hydrochloric Acid SCHEMBL29162507 | 0.83 | OPRL1 (0.36) | KDM4EGAAMAPK1HTTOPRM1 | |
| Fluoromethane SCHEMBL28832696 | 0.79 | PDE10A (0.34) | KDM4EGAAMAPK1HTTOPRM1 | |
| SCHEMBL3191675 | 0.77 | CYP11B2 (0.42) | KDM4EGAACYP11B2POLBCASP3 | |
| SCHEMBL9694895 | 0.77 | CYP11B2 (0.42) | KDM4EGAACYP11B2POLBCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2150 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12625150-B2 | Treatment of, and differential diagnosis between, ACTH-dependent Cushing's syndrome and ACTH-independent Cushing's syndrome | CORCEPT THERAPEUTICS INCORPORATED (US) | 2026-05-12 | — | — | US | claimed |
| EP-4076470-B1 | TREATMENT OF, AND DIFFERENTIAL DIAGNOSIS BETWEEN, ACTH-DEPENDENT CUSHING'S SYNDROME AND ACTH-INDEPENDENT CUSHING'S SYNDROME | CORCEPT THERAPEUTICS INC (US) | 2025-12-03 | — | — | EP | claimed |
| US-12263169-B2 | Methods of treating neuroepithelial tumors using selective glucocorticoid receptor modulators | CORCEPT THERAPEUTICS, INC. (US) | 2025-04-01 | — | — | US | claimed |
| US-20240261287-A1 | METHODS OF TREATING ANTIPSYCHOTIC-INDUCED WEIGHT GAIN WITH MIRICORILANT | CORCEPT THERAPEUTICS INCORPORATED (US) | 2024-08-08 | — | — | US | claimed |
| US-11903945-B2 | Methods of treating antipsychotic-induced weight gain with miricorilant | CORCEPT THERAPEUTICS INCORPORATED (US) | 2024-02-20 | — | — | US | claimed |
| US-11890289-B2 | Use of glucocorticoid receptor antagonists in combination with glucocorticoids to treat adrenal insufficiency | CORCEPT THERAPEUTICS, INC. (US) | 2024-02-06 | — | — | US | claimed |
| US-20240009194-A1 | METHODS OF TREATING NEUROEPITHELIAL TUMORS USING SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS | CORCEPT THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | US | claimed |
| US-11814563-B2 | Bioreachable chiral dopants for liquid crystal applications | ZYMERGEN INC. (US) | 2023-11-14 | — | — | US | claimed |
| US-20230358768-A1 | TREATMENT OF, AND DIFFERENTIAL DIAGNOSIS BETWEEN, ACTH-DEPENDENT CUSHING'S SYNDROME AND ACTH-INDEPENDENT CUSHING'S SYNDROME | CORCEPT THERAPEUTICS INCORPORATED (US) | 2023-11-09 | — | — | US | claimed |
| US-20230324415-A1 | METHOD FOR DIFFERENTIALLY DIAGNOSING ACTH-DEPENDENT CUSHING'S SYNDROME | CORCEPT THERAPEUTICS, INC. (US) | 2023-10-12 | — | — | US | claimed |
| CN-1420382-A | Liquid crystal display contg. chiral dopant | MERCK PATENT GMBH (DE) | 2003-05-28 | — | — | CN | claimed |
| US-6217792-B1 | Chiral dopants | MERCK PATENT GMBH (DE) | 2001-04-17 | — | — | US | claimed |
| US-5679282-A | Chiral 2,6-difluorobenzene derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-10-21 | — | — | US | claimed |
| EP-0408995-B1 | Liquid crystal medium with limited temperature-dependence of the d/p coefficient | MERCK PATENT GMBH (DE) | 1995-11-08 | — | — | EP | claimed |
| US-5155607-A | Optical modulation display device and display method using the same | FUJI XEROX CO., LTD. (JP) | 1992-10-13 | — | — | US | claimed |
| US-5139698-A | Achiral liquid crystal compound with doping component | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-08-18 | — | — | US | claimed |
| US-5043093-A | Liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-08-27 | — | — | US | claimed |
| EP-0408995-A2 | Liquid crystal medium with limited temperature-dependence of the d/p coefficient | MERCK PATENT GmbH (DE) | 1991-01-23 | — | — | EP | claimed |
| EP-0209622-B1 | HYDROTERPHENYLS | MERCK PATENT GmbH (DE) | 1989-06-07 | — | — | EP | claimed |
| US-4702562-A | MIXTURE-FOR MULTIPLEXING | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1987-10-27 | — | — | US | claimed |