SCHEMBL6126

SCHEMBL6126

O=C1CCC(C(=O)O)CC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 3/20 0.46
GABRD O14764 3/20 0.46
GABRA1 P14867 3/20 0.46
GABRB1 P18505 3/20 0.46
GABRG2 P18507 3/20 0.46
GABRB3 P28472 3/20 0.46
GABRA5 P31644 3/20 0.46
GABRA3 P34903 3/20 0.46
GABRA2 P47869 3/20 0.46
GABRB2 P47870 3/20 0.46
GABRA4 P48169 3/20 0.46
GABRE P78334 3/20 0.46
GABRA6 Q16445 3/20 0.46
GABRG1 Q8N1C3 3/20 0.46
GABRG3 Q99928 3/20 0.46
GABRQ Q9UN88 3/20 0.46
TSHR P16473 2/20 0.46
PMP22 Q01453 1/20 0.46
GABRR1 P24046 1/20 0.45
LMNA P02545 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28188006 0.91 ESR2 (0.40) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL27082408 0.91 ESR2 (0.40) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL14115855 0.85 MEN1 (0.46) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL29883233 0.84
SCHEMBL3295484 0.84
SCHEMBL51838 0.84
SCHEMBL8891557 0.84 TRIM24 (0.43) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL1666449 0.84
SCHEMBL29976399 0.84 GABRP (0.38) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL28501013 0.82 GABRP (0.41) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 921 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118221659-A Fluorescent probe for detecting superoxide anions and nitrosyl peroxide ions in targeting manner of golgi, preparation method and application thereof 南华大学 2024-06-21 CN claimed
CN-118146104-A Novel carbonyl functionalized proton type ionic liquid and preparation method and application thereof 南京大学 2024-06-07 CN claimed
CN-115093794-B Polysilicon polishing composition and application thereof 万华化学集团电子材料有限公司 2023-10-13 CN claimed
CN-116120213-A Synthesis method of trans-4- (tert-butoxycarbonylamino) cyclohexane carboxylic acid 重庆医药高等专科学校 2023-05-16 CN claimed
CN-116082192-A Preparation method of trans-4- (tert-butoxycarbonylamino) cyclohexane carboxylic acid 重庆医药高等专科学校 2023-05-09 CN claimed
CN-115850156-A Method for purifying difluoride compound 上海泰坦科技股份有限公司 2023-03-28 CN claimed
CN-112851923-B Modified polycaprolactone implant material and preparation method thereof, fiber and preparation method thereof, and patch 上海竞微扶生医学科技有限公司 2023-03-24 CN claimed
CN-113402428-B Preparation method of trans-4- (tert-butoxycarbonylamino) cyclohexanecarboxylic acid and intermediate thereof 重庆医药高等专科学校 2023-03-03 CN claimed
CN-115246787-A Meta-disubstituted compound, preparation thereof and application thereof in preventing and treating mosquito and plant pathogenic bacteria 吉林省达凯生物医药有限公司 2022-10-28 CN claimed
CN-115093794-A Polysilicon polishing composition and application thereof 万华化学集团电子材料有限公司 2022-09-23 CN claimed
WO-2003037870-A1 SUBSTITUTED 1H-QUINOLIN-2-ONE COMPOUNDS Grünenthal GmbH (DE) 2003-05-08 WO claimed
WO-2003037879-A1 SUBSTITUTED (1H)-QUINOXALIN-2-ONE COMPOUNDS AND SUBSTITUTED 4-ARYL- AND 4-HETEROARYLCYCLOHEXANE COMPOUNDS Grünenthal GmbH (DE) 2003-05-08 WO claimed
WO-2003037863-A2 SUBSTITUTED INDOLES, METHOD FOR PRODUCTION AND USE THEREOF FOR THE INHIBITION OF PAIN Grünenthal GmbH (DE) 2003-05-08 WO claimed
WO-2003037873-A1 SUBSTITUTED BENZO[B]AZEPIN-2-ONE COMPOUNDS Grünenthal GmbH (DE) 2003-05-08 WO claimed
EP-0240362-B1 PROCESS FOR THE PREPARATION OF 4'-HYDROXYBIPHENYL-4-CARBOXYLIC ACID MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-12-11 EP claimed
EP-0238305-B1 4,4-BIS(4-HYDROXYPHENYL)CYCLOHEXANECARBOXYLIC ACID DERIVATIVES AND PROCESS FOR PREPARING SAME MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-05-23 EP claimed
US-4814488-A STARTING MATERIALS FOR POLYMERS MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1989-03-21 US claimed
US-4755617-A Process for the preparation of 4'-hydroxybiphenyl-4-carboxyl acid MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1988-07-05 US claimed
EP-0240362-A2 Process for the preparation of 4'-hydroxybiphenyl-4-carboxylic acid MITSUI TOATSU CHEMICALS, Inc. (JP) 1987-10-07 EP claimed
EP-0238305-A1 4,4-Bis(4-hydroxyphenyl)cyclohexanecarboxylic acid derivatives and process for preparing same MITSUI TOATSU CHEMICALS, Inc. (JP) 1987-09-23 EP claimed