Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | QRFPR | Q96P65 | 8/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14394526 | 0.77 | KMT2A (0.45) | KMT2AQRFPRHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL11359171 | 0.77 | KMT2A (0.41) | KMT2AQRFPRHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL611355 | 0.76 | QRFPR (0.44) | KMT2AQRFPRTAAR1 | |
| SCHEMBL29943451 | 0.73 | TAAR1 (0.50) | SMN1; SMN2TAAR1MPOSLC6A4 | |
| SCHEMBL3678681 | 0.73 | TAAR1 (0.50) | SMN1; SMN2TAAR1MPOSLC6A4 | |
| SCHEMBL611198 | 0.72 | QRFPR (0.37) | KMT2AQRFPRHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL14261339 | 0.70 | QRFPR (0.39) | KMT2AQRFPRHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL612862 | 0.70 | QRFPR (0.39) | QRFPRHPGD | |
| SCHEMBL15270672 | 0.69 | KMT2A (0.64) | KMT2AQRFPRHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL6057114 | 0.69 | KMT2A (0.64) | KMT2AQRFPRHPGDL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120041038-A1 | AMINE DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ACUCELA INC. (US) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041038-A1 | AMINE DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | PDE6D, CLN6, AADAT | KMT2A 1037/4885QRFPR 3141/4885HPGD 312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.