Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMEL1 | Q495T6 | 7/20 | 0.68 |
| ▸ | MME | P08473 | 13/20 | 0.67 |
| ▸ | ACE | P12821 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3700012 | 1.00 | MMEL1 (0.68) | MMEL1MMEACE | |
| SCHEMBL12317482 | 0.89 | MMEL1 (0.55) | MMEL1MMEACE | |
| SCHEMBL9929532 | 0.88 | MME (0.70) | MME | |
| SCHEMBL9929535 | 0.88 | MME (0.70) | MME | |
| SCHEMBL2876097 | 0.84 | MMEL1 (0.65) | MMEL1MME | |
| SCHEMBL2876099 | 0.84 | MMEL1 (0.65) | MMEL1MME | |
| SCHEMBL18672529 | 0.83 | MMEL1 (0.66) | MMEL1MMEACE | |
| SCHEMBL12317322 | 0.83 | MMEL1 (0.66) | MMEL1MMEACE | |
| SCHEMBL17667996 | 0.83 | MME (0.79) | MMEL1MMEACE | |
| SCHEMBL18672747 | 0.83 | MME (0.79) | MMEL1MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2640375-A1 | METHOD OF TREATING CONTRAST-INDUCED NEPHROPATHY | Novartis AG (CH) | 2013-09-25 | — | — | EP | disclosed |
| WO-2012065958-A1 | METHOD OF TREATING CONTRAST-INDUCED NEPHROPATHY | NOVARTIS AG (CH) | 2012-05-24 | — | — | WO | disclosed |