Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 13/20 | 0.41 |
| ▸ | S100A4 | P26447 | 2/20 | 0.38 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25818473 | 0.84 | PGR (0.41) | PDK2S100A4AKR1A1AKR1B1PGR | |
| SCHEMBL26808479 | 0.82 | PDK2 (0.45) | PDK2S100A4AKR1A1AKR1B1KDM4E | |
| SCHEMBL19001688 | 0.82 | PDK2 (0.47) | PDK2S100A4AKR1A1AKR1B1 | |
| SCHEMBL23561599 | 0.81 | PDK2 (0.41) | PDK2S100A4AKR1A1AKR1B1MEN1 | |
| SCHEMBL20687345 | 0.81 | PDK2 (0.36) | PDK2S100A4AKR1A1AKR1B1 | |
| SCHEMBL20687350 | 0.79 | PDK2 (0.44) | PDK2S100A4AKR1A1AKR1B1 | |
| SCHEMBL20687340 | 0.77 | PDK2 (0.43) | PDK2S100A4AKR1A1AKR1B1 | |
| SCHEMBL23561471 | 0.77 | PDK2 (0.46) | PDK2AKR1A1AKR1B1MEN1KMT2A | |
| SCHEMBL23561609 | 0.77 | PDK2 (0.46) | PDK2AKR1A1AKR1B1MEN1KMT2A | |
| SCHEMBL23561288 | 0.76 | PDK2 (0.40) | PDK2S100A4AKR1A1AKR1B1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9991450-B2 | Spiro[cyclopenta[def]triphenylene-4,9′-fluorene] compound and organic light-emitting device having the same | CANON KABUSHIKI KAISHA (JP) | 2018-06-05 | — | — | US | disclosed |
| US-20130214267-A1 | SPIRO[CYCLOPENTA[def]TRIPHENYLENE-4,9'-FLUORENE] COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE HAVING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2013-08-22 | — | — | US | disclosed |
| US-20130214267-A1 | SPIRO[CYCLOPENTA[def]TRIPHENYLENE-4,9'-FLUORENE] COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE HAVING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2013-08-22 | — | — | US | disclosed |
| WO-2012056919-A1 | SPIRO[CYCLOPENTA[def]TRIPHENYLENE-4,9'-FLUORENE] COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE HAVING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2012-05-03 | — | — | WO | disclosed |