Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL120831 | 0.71 | KMT2A (0.33) | MAPTHPGDKMT2AALDH1A1MEN1 | |
| SCHEMBL6667605 | 0.71 | MAPT (0.42) | MAPTHPGDKMT2AALDH1A1MEN1 | |
| SCHEMBL11708444 | 0.68 | — | — | |
| SCHEMBL6129240 | 0.68 | APAF1 (0.31) | — | |
| SCHEMBL5264706 | 0.64 | NPC1 (0.37) | MAPTHPGDALDH1A1L3MBTL1 | |
| SCHEMBL6129226 | 0.63 | APAF1 (0.36) | MAPTHPGDKMT2AALDH1A1MEN1 | |
| SCHEMBL6668240 | 0.59 | MAPT (0.38) | MAPTHPGDKMT2AALDH1A1MEN1 | |
| SCHEMBL18769820 | 0.58 | MAPT (0.37) | MAPTHPGDKMT2AALDH1A1MEN1 | |
| SCHEMBL30912996 | 0.58 | APAF1 (0.35) | MAPTHPGDKMT2AALDH1A1MEN1 | |
| SCHEMBL6129248 | 0.56 | MAPT (0.45) | MAPTKMT2AALDH1A1MEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050000529-A1 | Method and compositions for imparting cooling effect to tobacco products | VECTOR TOBACCO INC. | 2005-01-06 | — | — | US | claimed |
| EP-1455609-A2 | METHOD AND COMPOSITIONS FOR IMPARTING COOLING EFFECT TO TOBACCO PRODUCTS | Vector Tobacco Inc. (US) | 2004-09-15 | — | — | EP | claimed |
| WO-2003053176-A2 | METHOD AND COMPOSITIONS FOR IMPARTING COOLING EFFECT TO TOBACCO PRODUCTS | VECTOR TOBACCO INC. (US) | 2003-07-03 | — | — | WO | claimed |
| US-20050000529-A1 | Method and compositions for imparting cooling effect to tobacco products | VECTOR TOBACCO INC. | 2005-01-06 | — | — | US | disclosed |