⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28619114 | 0.87 | TGFBR1 (0.32) | — | |
| SCHEMBL14782153 | 0.74 | NTRK2 (0.33) | — | |
| SCHEMBL27762530 | 0.73 | CA12 (0.38) | — | |
| SCHEMBL990556 | 0.72 | EPHX2 (0.31) | — | |
| SCHEMBL28271937 | 0.72 | EPHX2 (0.38) | — | |
| SCHEMBL2872137 | 0.72 | MEN1 (0.32) | — | |
| SCHEMBL10478376 | 0.71 | TGFBR1 (0.36) | — | |
| SCHEMBL10751597 | 0.71 | TGFBR1 (0.32) | — | |
| SCHEMBL6129398 | 0.71 | NTRK2 (0.31) | — | |
| SCHEMBL11231099 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1101101-A4 | METHOD FOR PRODUCING HYDROPHILIC MONOMERS AND USES THEREOF | BIOWHITTAKER MOLUCULAR APPLIC (US) | 2005-10-19 | — | — | EP | disclosed |
| US-6464850-B1 | CAPILLARY AND MICROCHANNEL ELECTROPHORESIS; HYDROLYTICALLY STABLE,HIGH RESOLUTION; HOMO OR COPOLYMER OF N-(2-HYDROXY ETHYL)ACRYLAMIDE, N-(2-HYDROXYETHYL) METHACRYLAMIDE, N,N-DI(HYDROXYALKYL)ACRYLAMIDE; SUPPRESSES ELECTROENDOOSMOSIS | BIOWHITTAKER MOLECULAR APPLICATIONS, INC. | 2002-10-15 | — | — | US | disclosed |
| EP-1101101-A1 | METHOD FOR PRODUCING HYDROPHILIC MONOMERS AND USES THEREOF | Biowhittaker Molucular Applications, Inc. (US) | 2001-05-23 | — | — | EP | disclosed |
| US-6117293-A | MONOMERS AND CROSSLINKER FOR PREPARING AN ELECTROPHORETIC GEL COMPRISES 75 WEIGHT % OR MORE OF HYDROPHILLIC MONOMER SELECTED FROM N-HYDROXYETHYL(METH)ACRYLAMIDE OR N,N-DIHYDROXYALKYL(METH)ACRYLAMIDE | BIOWHITTAKER MOLECULAR APPLICATIONS, INC. (US) | 2000-09-12 | — | — | US | disclosed |
| WO-2000007002-A1 | METHOD FOR PRODUCING HYDROPHILIC MONOMERS AND USES THEREOF | BIOWHITTAKER MOLECULAR APPLICATIONS, INC. (US) | 2000-02-10 | — | — | WO | disclosed |