Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | RGS12 | O14924 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1831639 | 0.82 | KDM4E (0.56) | USP2ALOX15HSD17B10KDM4EPKM | |
| SCHEMBL30544042 | 0.82 | KDM4E (0.56) | USP2ALOX15HSD17B10KDM4EPKM | |
| SCHEMBL7280604 | 0.79 | USP2 (0.50) | USP2ALOX15HSD17B10KDM4EPKM | |
| SCHEMBL5285947 | 0.79 | USP2 (0.50) | USP2ALOX15HSD17B10KDM4EPKM | |
| SCHEMBL645658 | 0.78 | USP2 (0.51) | USP2ALOX15HSD17B10KDM4EPKM | |
| SCHEMBL22090175 | 0.78 | USP2 (0.51) | USP2ALOX15HSD17B10KDM4EPKM | |
| SCHEMBL25408724 | 0.78 | USP2 (0.54) | USP2ALOX15HSD17B10KDM4EPKM | |
| SCHEMBL30605041 | 0.78 | USP2 (0.54) | USP2ALOX15HSD17B10KDM4EPKM | |
| SCHEMBL29031467 | 0.78 | USP2 (0.54) | USP2ALOX15HSD17B10KDM4EPKM | |
| SCHEMBL30605040 | 0.78 | USP2 (0.54) | USP2ALOX15HSD17B10KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282694-A4 | SULFAMIDE AND BIS-SULFAMIDE AMINO ACID DERIVATIVES AS INHIBITORS OF PROTEOLYTIC ENZYMES | SUPERGEN INC (US) | 2005-10-26 | — | — | EP | disclosed |
| EP-1282694-A1 | SULFAMIDE AND BIS-SULFAMIDE AMINO ACID DERIVATIVES AS INHIBITORS OF PROTEOLYTIC ENZYMES | Supergen, Inc. (US) | 2003-02-12 | — | — | EP | disclosed |
| WO-2001081561-A1 | SULFAMIDE AND BIS-SULFAMIDE AMINO ACID DERIVATIVES AS INHIBITORS OF PROTEOLYTIC ENZYMES | SUPERGEN, INC. (US) | 2001-11-01 | — | — | WO | disclosed |
| EP-1011668-A4 | 1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE DERIVATIVES | UNIV WICHITA STATE (US) | 2001-08-16 | — | — | EP | disclosed |
| EP-1011668-A1 | 1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE DERIVATIVES | THE WICHITA STATE UNIVERSITY (US) | 2000-06-28 | — | — | EP | disclosed |
| WO-1999009977-A9 | 1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE DERIVATIVES | UNIV WICHITA STATE (US) | 1999-06-24 | — | — | WO | disclosed |
| WO-1999009977-A1 | 1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE DERIVATIVES | WICHITA STATE UNIVERSITY (US) | 1999-03-04 | — | — | WO | disclosed |