Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | RGS12 | O14924 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5285947 | 1.00 | USP2 (0.50) | USP2MAPTPKMALOX15HIF1A | |
| SCHEMBL13957611 | 0.89 | USP2 (0.47) | USP2MAPTPKMALOX15HIF1A | |
| SCHEMBL1516481 | 0.89 | USP2 (0.47) | USP2MAPTPKMALOX15HIF1A | |
| SCHEMBL4626004 | 0.84 | MAPT (0.47) | USP2MAPTPKMALOX15HIF1A | |
| SCHEMBL43843 | 0.84 | MAPT (0.47) | USP2MAPTPKMALOX15HIF1A | |
| SCHEMBL158168 | 0.84 | MAPT (0.47) | USP2MAPTPKMALOX15HIF1A | |
| SCHEMBL30544071 | 0.83 | SLC7A5 (0.48) | USP2MAPTPKMALOX15HIF1A | |
| SCHEMBL5672308 | 0.81 | USP2 (0.50) | USP2MAPTPKMALOX15HIF1A | |
| SCHEMBL28551296 | 0.81 | USP2 (0.50) | USP2MAPTPKMALOX15HIF1A | |
| SCHEMBL5672304 | 0.81 | USP2 (0.50) | USP2MAPTPKMALOX15HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250179465-A1 | SITE-SPECIFIC ENCODING OF FLUORINATED PHENYLALANINE RESIDUES IN BACTERIAL AND MAMMALIAN CELLS | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2025-06-05 | — | — | US | claimed |
| EP-4479526-A1 | SITE-SPECIFIC ENCODING OF FLUORINATED PHENYLALANINE RESIDUES IN BACTERIAL AND MAMMALIAN CELLS | University of Iowa Research Foundation (US) | 2024-12-25 | — | — | EP | claimed |
| WO-2023158761-A1 | SITE-SPECIFIC ENCODING OF FLUORINATED PHENYLALANINE RESIDUES IN BACTERIAL AND MAMMALIAN CELLS | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2023-08-24 | — | — | WO | claimed |
| US-20250179465-A1 | SITE-SPECIFIC ENCODING OF FLUORINATED PHENYLALANINE RESIDUES IN BACTERIAL AND MAMMALIAN CELLS | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2025-06-05 | — | — | US | disclosed |
| EP-4479526-A1 | SITE-SPECIFIC ENCODING OF FLUORINATED PHENYLALANINE RESIDUES IN BACTERIAL AND MAMMALIAN CELLS | University of Iowa Research Foundation (US) | 2024-12-25 | — | — | EP | disclosed |
| WO-2023158761-A1 | SITE-SPECIFIC ENCODING OF FLUORINATED PHENYLALANINE RESIDUES IN BACTERIAL AND MAMMALIAN CELLS | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2023-08-24 | — | — | WO | disclosed |
| US-20230129095-A1 | PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES | PROTAGONIST THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | US | disclosed |
| US-20230129095-A1 | PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES | PROTAGONIST THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | US | disclosed |
| US-4766110-A | INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS | RYAN JAMES W (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0073143-B1 | NOVEL COMPLEX AMIDO AND IMIDO DERIVATIVES OF CARBOXYALKYL PEPTIDES AND THIOETHERS AND ETHERS OF PEPTIDES | Ryan, James Walter (US) | 1985-11-21 | — | — | EP | disclosed |
| EP-0073143-A2 | Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides | Ryan, James Walter (US) | 1983-03-02 | — | — | EP | disclosed |
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230129095-A1 | PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES | IL23R, IL1RN, VIP | USP2 2702/4885MAPT 2759/4885PKM 4457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.