Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUT8 | Q9BYC5 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 5/20 | 0.41 |
| ▸ | CHAT | P28329 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7197090 | 0.81 | FUT8 (0.72) | FUT8MEN1KMT2ATHRBCHAT | |
| SCHEMBL17190771 | 0.81 | FUT8 (0.69) | FUT8MEN1KMT2ATHRBCYP1A2 | |
| SCHEMBL9999814 | 0.80 | FUT8 (0.60) | FUT8NR4A1TTRFABP4CCNA2 | |
| SCHEMBL9999813 | 0.80 | FUT8 (0.63) | FUT8NR4A1TTRFABP4CCNA2 | |
| SCHEMBL25592390 | 0.79 | FUT8 (0.54) | FUT8MEN1KMT2ATHRBCHAT | |
| SCHEMBL20390572 | 0.78 | FUT8 (0.81) | FUT8NR4A1MEN1KMT2ATHRB | |
| SCHEMBL11995621 | 0.78 | FUT8 (0.55) | FUT8MEN1KMT2ACHATCA12 | |
| SCHEMBL19754268 | 0.77 | FUT8 (0.69) | FUT8MEN1KMT2ATHRBCYP1A2 | |
| SCHEMBL25592397 | 0.76 | FUT8 (0.54) | FUT8MEN1KMT2ATHRBCHAT | |
| SCHEMBL12589955 | 0.75 | FUT8 (0.67) | FUT8MEN1KMT2ATHRBCHAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161564-A4 | SCREENING OF ANTIVIRAL COMPOUNDS TARGETED TO THE HIV-1 gp41 CORE STRUCTURE | NEW YORK BLOOD CT INC (US) | 2005-03-30 | — | — | EP | disclosed |
| EP-1161564-A1 | SCREENING OF ANTIVIRAL COMPOUNDS TARGETED TO THE HIV-1 gp41 CORE STRUCTURE | New York Blood Center, Inc. (US) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055377-A1 | SCREENING OF ANTIVIRAL COMPOUNDS TARGETED TO THE HIV-1 gp41 CORE STRUCTURE | NEW YORK BLOOD CENTER, INC. (US) | 2000-09-21 | — | — | WO | disclosed |