SCHEMBL9999813

SCHEMBL9999813

O=S(=O)(O)c1cc2cccc(Nc3nc(Cl)nc(Nc4ccccc4)n3)c2c(O)c1N=Nc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FUT8 Q9BYC5 1/20 0.63
▸ NR4A1 P22736 1/20 0.48
▸ TTR P02766 1/20 0.47
▸ FABP4 P15090 1/20 0.47
▸ CCNA2 P20248 1/20 0.47
▸ CDK2 P24941 1/20 0.47
▸ MAPK14 Q16539 1/20 0.47
▸ ENPP2 Q13822 3/20 0.45
▸ PRMT1 Q99873 2/20 0.43
▸ CARM1 Q86X55 1/20 0.43
▸ PRMT3 O60678 1/20 0.42
▸ EP300 Q09472 1/20 0.42
▸ PRMT6 Q96LA8 1/20 0.42
▸ MAPK1 P28482 2/20 0.41
▸ MEN1 O00255 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ MAPT P10636 1/20 0.41
▸ CA12 O43570 1/20 0.40
▸ CA1 P00915 1/20 0.40
▸ CA2 P00918 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9999814 0.95 FUT8 (0.60) FUT8NR4A1TTRFABP4CCNA2
SCHEMBL20390572 0.85 FUT8 (0.81) FUT8NR4A1ENPP2PRMT1CARM1
SCHEMBL17190771 0.84 FUT8 (0.69) FUT8ENPP2PRMT1CARM1PRMT3
SCHEMBL16557837 0.84 FUT8 (0.53) FUT8NR4A1ENPP2PRMT1CARM1
SCHEMBL6808077 0.83 FUT8 (0.73) FUT8ENPP2PRMT1CARM1PRMT3
SCHEMBL3697366 0.83 FUT8 (0.73) FUT8ENPP2PRMT1CARM1PRMT3
SCHEMBL3697372 0.83 FUT8 (0.73) FUT8ENPP2PRMT1CARM1PRMT3
SCHEMBL7197090 0.81 FUT8 (0.72) FUT8ENPP2PRMT1CARM1PRMT3
SCHEMBL10104422 0.81 FUT8 (0.64) FUT8ENPP2PRMT1CARM1PRMT3
SCHEMBL10782738 0.81 FUT8 (0.70) FUT8ENPP2PRMT1CARM1PRMT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120047663-A1 Method for reactive dyeing of leather EVERLIGHT USA, INC. (US) 2012-03-01 — — US disclosed
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