Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL198129 | 0.84 | CES1 (0.44) | CES2CES1TSHRALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL16599967 | 0.82 | CES1 (0.42) | CES2CES1TSHRALDH1A1TP53 | |
| SCHEMBL7028156 | 0.81 | CES1 (0.41) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL8089101 | 0.80 | HSP90AA1 (0.45) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL891395 | 0.79 | CES2 (0.46) | CES2CES1TSHRALDH1A1 | |
| Propene SCHEMBL28322952 | 0.78 | CES1 (0.38) | CES2CES1TSHRALDH1A1TP53 | |
| SCHEMBL2957228 | 0.77 | CES2 (0.48) | CES2CES1TSHRALDH1A1 | |
| SCHEMBL11761845 | 0.77 | CES2 (0.48) | CES2CES1TSHRALDH1A1 | |
| SCHEMBL1760742 | 0.77 | CES2 (0.48) | CES2CES1TSHRALDH1A1 | |
| SCHEMBL16538567 | 0.77 | CES2 (0.48) | CES2CES1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210034-A4 | HYDROPHILIC BIOMEDICAL COMPOSITIONS | COMMW SCIENT ANDINDUSTRIAL RES (AU) | 2005-02-02 | — | — | EP | disclosed |
| EP-1210034-A1 | HYDROPHILIC BIOMEDICAL COMPOSITIONS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001008604-A1 | HYDROPHILIC BIOMEDICAL COMPOSITIONS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2001-02-08 | — | — | WO | disclosed |