Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL8723413 | 0.96 | — | — | |
| Glycine SCHEMBL8095196 | 0.96 | — | — | |
| Glycine SCHEMBL27597443 | 0.96 | GLRA1 (0.83) | — | |
| Glycine SCHEMBL27806302 | 0.92 | — | — | |
| Glycine SCHEMBL27197 | 0.92 | — | — | |
| Glycine SCHEMBL27299028 | 0.92 | — | — | |
| Glycine SCHEMBL6258843 | 0.92 | GLRA1 (0.91) | — | |
| Glycine SCHEMBL2184511 | 0.92 | — | — | |
| Glycine SCHEMBL8627101 | 0.88 | — | — | |
| Glycine SCHEMBL6853447 | 0.88 | GLRA1 (0.83) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282593-A4 | BIOCIDAL COMPOSITION WHICH IS AN AQUEOUS SOLUTION OF HYDROXYMETHYLAMINOACETATE | ISP INVESTMENTS INC (US) | 2005-01-19 | — | — | EP | disclosed |
| EP-1282593-A1 | BIOCIDAL COMPOSITION WHICH IS AN AQUEOUS SOLUTION OF HYDROXYMETHYLAMINOACETATE | ISP INVESTMENTS INC. (US) | 2003-02-12 | — | — | EP | disclosed |
| WO-2001087820-A1 | BIOCIDAL COMPOSITION WHICH IS AN AQUEOUS SOLUTION OF HYDROXYMETHYLAMINOACETATE | ISP INVESTMENTS INC. (US) | 2001-11-22 | — | — | WO | disclosed |