Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL8723413 | 1.00 | — | — | |
| Glycine SCHEMBL6130031 | 0.96 | — | — | |
| Glycine SCHEMBL20295 | 0.92 | — | — | |
| Glycine SCHEMBL8585762 | 0.92 | GLRA1 (0.83) | — | |
| Glycine SCHEMBL21879657 | 0.92 | GLRA1 (0.83) | — | |
| Glycine SCHEMBL6853447 | 0.92 | GLRA1 (0.83) | — | |
| Glycine SCHEMBL6239942 | 0.92 | GLRA1 (0.83) | — | |
| Glycine SCHEMBL5569329 | 0.92 | — | — | |
| Glycine SCHEMBL391027 | 0.91 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL6163 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102898467-A | One-pot synthesis method for glyphosate from chloroacetic acid | UNIV TAIYUAN TECHNOLOGY | 2013-01-30 | — | — | CN | claimed |
| CN-100513410-C | Production of glyphosate by glycine method | YINGLI CHEMICAL TECHNOLOGY CO (CN) | 2009-07-15 | — | — | CN | claimed |
| CN-1939926-A | Production of glyphosate by glycine method | QINGHUAZIGUANG YINGLI CHEMICAL (CN) | 2007-04-04 | — | — | CN | claimed |
| CN-109675423-A | A kind of formaldehyde scavenger and preparation method thereof | 无限极（中国）有限公司 | 2019-04-26 | — | — | CN | disclosed |
| CN-108690071-A | A kind of chloroacetic acid is the technique of the alkyl esterification method synthesizing glyphosate of raw material | 湖北泰盛化工有限公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-108130355-A | A kind of collagen polypeptide rich in glycine and formaldehyde scavenger prepared therefrom | 华南理工大学 | 2018-06-08 | — | — | CN | disclosed |
| CN-102898467-A | One-pot synthesis method for glyphosate from chloroacetic acid | UNIV TAIYUAN TECHNOLOGY | 2013-01-30 | — | — | CN | disclosed |
| CN-101891763-A | Production method of N-(phosphonomethyl)glycine | QIKUI LI | 2010-11-24 | — | — | CN | disclosed |
| CN-100513410-C | Production of glyphosate by glycine method | YINGLI CHEMICAL TECHNOLOGY CO (CN) | 2009-07-15 | — | — | CN | disclosed |
| CN-100500678-C | Process of glycine method for preparing glyphosate | CHONGQING SANXIA YINGLI CHEMIC (CN) | 2009-06-17 | — | — | CN | disclosed |
| CN-1962672-A | Process of glycine method for preparing glyphosate | CHONGQING SANXIA YINGLI CHEMIC (CN) | 2007-05-16 | — | — | CN | disclosed |
| US-5041628-A | Method for the preparation of N-phosphonomethyl glycine | FINCHIMICA S.P.A. (IT) | 1991-08-20 | — | — | US | disclosed |
| EP-0402887-A1 | A method for the preparation of N-phosphonomethyl glycine | FINCHIMICA S.p.A. (IT) | 1990-12-19 | — | — | EP | disclosed |
| US-4486359-A | Process for the preparation of N-phosphonomethyl-glycine | ALKALOIDA VEGYESZETI GYAR (HU) | 1984-12-04 | — | — | US | disclosed |
| EP-0032500-B1 | PRESERVATIVE COMPOSITIONS | SUTTON LABORATORIES, INC. (US) | 1984-09-26 | — | — | EP | disclosed |
| US-4337269-A | HYDROXYMETHYLAMINOACETIC ACID, ESTER OR SALT | SUTTON LABORATORIES, INC. (US) | 1982-06-29 | — | — | US | disclosed |
| EP-0032500-A4 | PRESERVATIVE COMPOSITIONS. | SUTTON LAB INC (US) | 1981-11-24 | — | — | EP | disclosed |
| EP-0032500-A1 | PRESERVATIVE COMPOSITIONS. | SUTTON LAB INC (US) | 1981-07-29 | — | — | EP | disclosed |
| WO-1981000188-A1 | PRESERVATIVE COMPOSITIONS | SUTTON LAB INC (US) | 1981-02-05 | — | — | WO | disclosed |
| US-4171225-A | HYDROXYMETHYL AMINO ALKYLCARBOXYLIC OR -SULFONIC ACID ALKALI SALTS AS STABLE REDUCING AGENTS | U.S. PHILIPS CORPORATION (US) | 1979-10-16 | — | — | US | disclosed |