Phenylalanine

Phenylalanine

SCHEMBL6130121

C[C@H](N)C(=O)O[C@H](C)[C@H](N)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 8/20 0.61
ALPI P09923 1/20 0.61
PKM P14618 1/20 0.61
PTGS1 P23219 1/20 0.61
XIAP P98170 1/20 0.61
SLC1A3 P43003 2/20 0.49
SLC1A2 P43004 2/20 0.49
SLC1A1 P43005 2/20 0.49
NOS3 P29474 1/20 0.44
NOS1 P29475 1/20 0.44
NOS2 P35228 1/20 0.44
TPH1 P17752 1/20 0.43
SLC15A1 P46059 2/20 0.43
LTA4H P09960 1/20 0.43
ANPEP P15144 1/20 0.43
RNPEP Q9H4A4 1/20 0.43
DNPEP Q9ULA0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylalanine SCHEMBL9216397 0.90 SLC7A5 (0.59) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL4586624 0.90 ALPI (0.57) SLC7A5ALPIPKMPTGS1XIAP
Tyrosine SCHEMBL16820323 0.89 SLC7A5 (0.63) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL6130124 0.84 SLC7A5 (0.51) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL6033327 0.82 SLC7A5 (0.85) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL37367 0.82 SLC7A5 (0.85) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL3486837 0.82 SLC7A5 (0.85) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL2063249 0.82 SLC7A5 (0.85) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL6535507 0.82 SLC7A5 (0.85) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL28229442 0.82 SLC7A5 (0.85) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1315752-A4 MODIFIED PROTEINS, ISOLATED NOVEL PEPTIDES, AND USES THEREOF UNIV AUSTRALIAN (AU) 2005-07-06 EP disclosed
US-20040091964-A1 Modified proteins, isolated novel peptides,and uses thereof BOARD PHILLIP (AU) 2004-05-13 US disclosed
EP-1315752-A1 MODIFIED PROTEINS, ISOLATED NOVEL PEPTIDES, AND USES THEREOF THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 2003-06-04 EP disclosed
WO-2002018438-A9 MODIFIED PROTEINS, ISOLATED NOVEL PEPTIDES, AND USES THEREOF UNIV AUSTRALIAN (AU) 2002-05-30 WO disclosed
WO-2002018438-A1 MODIFIED PROTEINS, ISOLATED NOVEL PEPTIDES, AND USES THEREOF THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 2002-03-07 WO disclosed