SCHEMBL6130179

SCHEMBL6130179

Cc1cccc2c1sc1c(C)cccc12.Cc1cccc2c1sc1cccc(C)c12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.44
CYP1A2 P05177 2/20 0.44
ALDH1A1 P00352 5/20 0.41
MAPT P10636 5/20 0.41
POLB P06746 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
HCRTR1 O43613 1/20 0.41
LMNA P02545 1/20 0.41
GPR3 P46089 1/20 0.37
KDM4E B2RXH2 1/20 0.37
PLAU P00749 1/20 0.37
IDO1 P14902 1/20 0.36
TDO2 P48775 1/20 0.36
PARP14 Q460N5 1/20 0.35
TP53 P04637 1/20 0.35
ALOX5 P09917 1/20 0.34
APP P05067 1/20 0.34
CHRM2 P08172 1/20 0.34
HTR1A P08908 1/20 0.34
ADRA2A P08913 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29735389 0.96 CYP2A6 (0.48) CYP2A6CYP1A2ALDH1A1MAPTPOLB
SCHEMBL939375 0.96 CYP2A6 (0.48) CYP2A6CYP1A2ALDH1A1MAPTPOLB
SCHEMBL142551 0.89 CYP1A2 (0.55) CYP2A6CYP1A2ALDH1A1MAPTPOLB
SCHEMBL29364650 0.89 CYP1A2 (0.55) CYP2A6CYP1A2ALDH1A1MAPTPOLB
SCHEMBL731864 0.87 GPR3 (0.54) CYP2A6CYP1A2ALDH1A1MAPTPOLB
SCHEMBL29388065 0.87 GPR3 (0.54) CYP2A6CYP1A2ALDH1A1MAPTPOLB
Hydrogen Sulfide SCHEMBL28590036 0.86 CYP1A2 (0.52) CYP2A6CYP1A2ALDH1A1MAPTPOLB
SCHEMBL15785773 0.86 GPR3 (0.48) CYP2A6CYP1A2ALDH1A1MAPTPOLB
Dibenzothiophene SCHEMBL17841704 0.85 GPR3 (0.58) CYP2A6CYP1A2ALDH1A1MAPTPOLB
Dibenzothiophene SCHEMBL6130180 0.85 GPR3 (0.58) CYP2A6CYP1A2ALDH1A1MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1335962-A4 OXIDATIVE DESULFURIZATION OF FOSSIL FUELS WITH ULTRASOUND SULPHCO INC (US) 2005-01-19 EP disclosed
EP-1335962-A1 OXIDATIVE DESULFURIZATION OF FOSSIL FUELS WITH ULTRASOUND Sulphco.Inc. (US) 2003-08-20 EP disclosed
WO-2002026916-A1 OXIDATIVE DESULFURIZATION OF FOSSIL FUELS WITH ULTRASOUND SULPHCO. INC. (US) 2002-04-04 WO disclosed