SCHEMBL6130183

SCHEMBL6130183

NCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.41
GSTK1 Q9Y2Q3 1/20 0.41
GLO1 Q04760 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ITGB3 P05106 4/20 0.34
ITGB1 P05556 3/20 0.34
ITGAV P06756 3/20 0.34
ITGA5 P08648 3/20 0.34
MDM4 O15151 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
PTGS2 P35354 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ECE1 P42892 4/20 0.34
TERT O14746 1/20 0.34
MDM2 Q00987 2/20 0.33
GRIA1 P42261 1/20 0.33
GRIA3 P42263 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6757860 1.00 PTGS1 (0.41) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL6675010 1.00 PTGS1 (0.41) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL7257306 1.00 PTGS1 (0.41) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL8214832 1.00 PTGS1 (0.41) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL8213852 1.00 PTGS1 (0.41) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL7571368 1.00 PTGS1 (0.41) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL8436887 1.00 PTGS1 (0.41) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL18396457 1.00 PTGS1 (0.41) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL6823837 1.00 PTGS1 (0.41) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL7576676 1.00 PTGS1 (0.41) PTGS1GSTK1GLO1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1337643-A4 MANIPULATION OF PLANT LIFE CYCLES AND/OR GROWTH PHASES MOLECULAR PLANT BREEDING NOMINEES LTD (AU) 2005-08-10 EP claimed
EP-1337643-A1 MANIPULATION OF PLANT LIFE CYCLES AND/OR GROWTH PHASES Molecular Plant Breeding Nominees Ltd (AU) 2003-08-27 EP claimed
WO-2002038768-A1 MANIPULATION OF PLANT LIFE CYCLES AND/OR GROWTH PHASES MOLECULAR PLANT BREEDING NOMINEES LTD (AU) 2002-05-16 WO claimed
US-5686564-A Peptide derivatives corresponding to the carboxy terminal sequence of hirudin NOVARTIS CORPORATION (US) 1997-11-11 US claimed
EP-0637318-A1 PEPTIDE DERIVATIVES CORRESPONDING TO THE CARBOXY TERMINAL SEQUENCE OF HIRUDIN Novartis AG (CH) 1995-02-08 EP claimed
WO-1993022344-A1 PEPTIDE DERIVATIVES CORRESPONDING TO THE CARBOXY TERMINAL SEQUENCE OF HIRUDIN CIBA-GEIGY AG (CH) 1993-11-11 WO claimed
EP-0560913-A1 BIFUNCTIONAL INHIBITORS OF THROMBIN AND PLATELET ACTIVATION BIOGEN, INC. (US) 1993-09-22 EP claimed
WO-1992010575-A1 BIFUNCTIONAL INHIBITORS OF THROMBIN AND PLATELET ACTIVATION BIOGEN, INC. (US) 1992-06-25 WO claimed
CN-117098843-A Subtilisin variants and uses thereof 费森尤斯卡比有限公司 2023-11-21 CN disclosed
CN-116981680-A Compositions and methods for peptide production 生物催化剂有限责任公司 2023-10-31 CN disclosed
CN-116790555-A Development of RNA-targeted Gene editing tools 上海鲸奇生物科技有限公司 2023-09-22 CN disclosed
CN-114106112-B Truncated expressed Mandarin infectious spleen and kidney necrosis virus main capsid protein and application thereof 西北农林科技大学 2023-07-07 CN disclosed
US-11643439-B2 Multi-target compound with anticoagulation and antiplatelet activity, preparation method therefor, and use thereof SHAANXI MICOT TECHNOLOGY LIMITED COMPANY (CN) 2023-05-09 US disclosed
CN-108602762-B Linker molecules and their use in methods for purifying peptides 贝兰迪克有限责任公司 2022-12-16 CN disclosed
EP-0713496-A1 FIBRIN-TARGETED INHIBITORS OF THROMBIN PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1996-05-29 EP disclosed
EP-0637318-A1 PEPTIDE DERIVATIVES CORRESPONDING TO THE CARBOXY TERMINAL SEQUENCE OF HIRUDIN Novartis AG (CH) 1995-02-08 EP disclosed
WO-1994025491-A1 FIBRIN-TARGETED INHIBITORS OF THROMBIN PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1994-11-10 WO disclosed
WO-1993022344-A1 PEPTIDE DERIVATIVES CORRESPONDING TO THE CARBOXY TERMINAL SEQUENCE OF HIRUDIN CIBA-GEIGY AG (CH) 1993-11-11 WO disclosed
EP-0560913-A1 BIFUNCTIONAL INHIBITORS OF THROMBIN AND PLATELET ACTIVATION BIOGEN, INC. (US) 1993-09-22 EP disclosed
WO-1992010575-A1 BIFUNCTIONAL INHIBITORS OF THROMBIN AND PLATELET ACTIVATION BIOGEN, INC. (US) 1992-06-25 WO disclosed