SCHEMBL8214832

SCHEMBL8214832

NCC(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)NCC(=O)NCC(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.41
GSTK1 Q9Y2Q3 1/20 0.41
GLO1 Q04760 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ITGB3 P05106 4/20 0.34
ITGB1 P05556 3/20 0.34
ITGAV P06756 3/20 0.34
ITGA5 P08648 3/20 0.34
MDM4 O15151 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
PTGS2 P35354 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ECE1 P42892 4/20 0.34
TERT O14746 1/20 0.34
MDM2 Q00987 2/20 0.33
GRIA1 P42261 1/20 0.33
GRIA3 P42263 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6757860 1.00 PTGS1 (0.41) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL6675010 1.00 PTGS1 (0.41) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL7257306 1.00 PTGS1 (0.41) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL8213852 1.00 PTGS1 (0.41) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL7571368 1.00 PTGS1 (0.41) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL8436887 1.00 PTGS1 (0.41) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL6130183 1.00 PTGS1 (0.41) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL18396457 1.00 PTGS1 (0.41) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL6823837 1.00 PTGS1 (0.41) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL7576676 1.00 PTGS1 (0.41) PTGS1GSTK1GLO1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110291193-B Production of desaturated fatty alcohols and desaturated fatty alcohol acetates in yeast 丹麦科技大学 2024-03-08 CN disclosed
CN-112961843-B Plant immunoregulation related protein and application thereof 浙江大学 2023-01-03 CN disclosed
CN-115103900-A Yeast cells and methods for producing E8, E10-dodecadienyl coenzyme A, alexan and derivatives thereof 费罗生物公司 2022-09-23 CN disclosed
CN-113092772-A Application of urine cadherin subgroup SA-2 and polypeptide fragment thereof in allergic diseases 首都医科大学附属北京世纪坛医院 2021-07-09 CN disclosed
CN-112961843-A Plant immunoregulation related protein and application thereof 浙江大学 2021-06-15 CN disclosed
CN-110691509-A Method for improving plant traits 植物ARC生物技术有限公司 2020-01-14 CN disclosed
CN-110591991-A Recombinant bacterial host cells for protein expression UCB医药有限公司 2019-12-20 CN disclosed
CN-110291193-A Desaturation fatty alcohol and desaturation fatty acyl group acetic acid esters are generated in yeast 丹麦科技大学 2019-09-27 CN disclosed
CN-107674882-A Spatially modified gene expression in plant 加利福尼亚大学董事会 2018-02-09 CN disclosed
CN-107475168-A High foaming Shigella bacterial strain 全球健康GSK疫苗学院有限公司 2017-12-15 CN disclosed
CN-1437652-A Compounds and methods for treatment and diagnosis of chlamydial infection CORIXA CORP (US) 2003-08-20 CN disclosed
US-6153580-A FOR GENERATING AN IMMUNE RESPONSE IN HOST LOOSMORE SHEENA M (CA) 2000-11-28 US disclosed
US-6147057-A IMMUNOGENIC COMPOSITION CONNAUGHT LABORATORIES LIMITED (CA) 2000-11-14 US disclosed
US-6114125-A DETECTION BACTERIAL PARASITE POLYPEPTIDE IN SAMPLE; IMMUNIZING A MAMMAL, ISOLATING ANTIBODIES, INCUBATING SAMPLE WITH ANTIBODIES, DETECTING COMPLEXES CONNAUGHT LABORATORIES LIMITED (CA) 2000-09-05 US disclosed
US-6025342-A Analog of Haemophilus Hin47 with reduced protease activity CONNAUGHT LABORATORIES LIMITED (CA) 2000-02-15 US disclosed
US-6020183-A Analog of haemophilus Hin47 with reduced protease activity CONNAUGHT LABORATRIES LIMITED (CA) 2000-02-01 US disclosed
US-6004794-A NUCLEIC ACIDS ENCODING AN ENZYME WHICH BINDS A PRESENILIN PROTEIN INVOLVED IN NEURODEGENERATION SUCH AS ALZHEIMER'S DISEASE; FOR DIAGNOSIS AND THERAPY INCLUDING GENE THERAPY OF NERVOUS SYSTEM DISORDERS SMITHKLINE BEECHAM CORPORATION (US) 1999-12-21 US disclosed
US-5980907-A USE IN IMMUNOPROPHYLAXIS GLAXO WELLCOME INC. (US) 1999-11-09 US disclosed
US-5981503-A EFFECTING SITE-DIRECTED MUTAGENESIS OF THE HIN47 GENE TO REMOVE OR REPLACE A NUCLEOTIDE SEQUENCE ENCODING ATLEAST ONE AMINO ACID AND PRODUCE A MUTATED HAEMOPHILUS INFUENZA HIN 47, INTRODUCING TO THE CELL FOR GROWING A TRANSFORMED CELL CONNAUGHT LABORATORIES LIMITED (CA) 1999-11-09 US disclosed
CN-1136328-A Haemophilus Hin47 analogs with reduced protease activity CONNAUGHT LAB (US) 1996-11-20 CN disclosed