SCHEMBL6130641

SCHEMBL6130641

FC(F)(F)CCC1=CCc2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.46
NQO2 P16083 1/20 0.34
MTNR1A P48039 1/20 0.34
MTNR1B P49286 1/20 0.34
HTR7 P34969 1/20 0.33
SIGMAR1 Q99720 1/20 0.31
CYP2D6 P10635 1/20 0.30
HRH1 P35367 1/20 0.30
NAMPT P43490 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6664305 0.83 HTR6 (0.42) HTR6NQO2MTNR1AMTNR1BNAMPT
SCHEMBL31121639 0.82 HTR6 (0.56) HTR6NQO2MTNR1AMTNR1BHTR7
SCHEMBL2338975 0.82 HTR6 (0.56) HTR6NQO2MTNR1AMTNR1BHTR7
SCHEMBL3874874 0.79 HTR6 (0.53) HTR6NQO2MTNR1AMTNR1BHTR7
SCHEMBL3868123 0.79 HTR6 (0.53) HTR6NQO2MTNR1AMTNR1BHTR7
SCHEMBL1822774 0.76 HTR6 (0.50) HTR6HTR7SIGMAR1
SCHEMBL31547775 0.76 HTR6 (0.59) HTR6HTR7SIGMAR1HRH1
SCHEMBL8952468 0.76 HTR6 (0.54) HTR6NQO2MTNR1AMTNR1BHTR7
SCHEMBL5859128 0.76 HTR6 (0.50) HTR6NQO2MTNR1AMTNR1BHTR7
SCHEMBL3862943 0.76 HTR6 (0.59) HTR6HTR7SIGMAR1HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023080938-A1 CATALYST COMPONENTS FOR THE PREPARATION OF HIGHLY ISOTACTACTIC POLYPROPYLENE POLYMER WITH BROAD MOLECULAR WEIGHT DISTRIBUTION FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2023-05-11 WO disclosed
EP-1458810-A4 HIGH MODULUS, HIGH DUCTILITY POLYOLEFINS HUNTSMAN POLYMERS CORP (US) 2005-02-09 EP disclosed
EP-1458810-A1 HIGH MODULUS, HIGH DUCTILITY POLYOLEFINS Huntsman Polymers Corporation, Legal Department (US) 2004-09-22 EP disclosed
WO-2003031513-A1 HIGH MODULUS, HIGH DUCTILITY POLYOLEFINS HUNTSMAN POLYMERS CORPORATION (US) 2003-04-17 WO disclosed