Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 9/20 | 0.37 |
| ▸ | MME | P08473 | 8/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2352396 | 0.85 | ECE1 (0.42) | ECE1MMEACE2ELANE | |
| SCHEMBL2933823 | 0.84 | PRTN3 (0.44) | ECE1MMEPRTN3ELANE | |
| SCHEMBL2939670 | 0.84 | PPARG (0.34) | — | |
| SCHEMBL2354373 | 0.83 | SYK (0.43) | ECE1MMEACE2PRTN3ELANE | |
| SCHEMBL4710021 | 0.77 | PRTN3 (0.44) | ITGB3ITGAVPRTN3ELANE | |
| SCHEMBL2939235 | 0.77 | PRTN3 (0.46) | PRTN3ELANE | |
| SCHEMBL2940407 | 0.75 | PPARG (0.35) | PRTN3 | |
| SCHEMBL2936801 | 0.72 | S1PR1 (0.35) | — | |
| SCHEMBL2354094 | 0.72 | ACE2 (0.42) | ECE1MMEACE2 | |
| SCHEMBL2350988 | 0.71 | ELANE (0.52) | ECE1MMEACE2PRTN3ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497300-A2 | PLASMA CARBOXYPEPTIDASE B INHIBITORS | Schering Aktiengesellschaft (DE) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003080631-A2 | PLASMA CARBOXYPEPTIDASE B INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-02 | — | — | WO | disclosed |