PRTN3

Myeloblastin · P24158 · PRTN3 on Sugi Atlas →

6,489 patent compounds predicted against PRTN3, 4,090 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Acetic Acid (SCHEMBL1275199)	0.79	12/20
Sivelestat (SCHEMBL123221)	0.71	12/20
Sivelestat (SCHEMBL566914)	0.69	12/20
Sivelestat (SCHEMBL597819)	0.68	12/20
Sivelestat (SCHEMBL1499929)	0.68	12/20
SCHEMBL2740677	0.43	6/20
SCHEMBL3272714	0.49	4/20
Ethadione (SCHEMBL35279)	0.55	3/20
SCHEMBL1973323	0.53	3/20
SCHEMBL769767	0.51	3/20
Hydrochloric Acid (SCHEMBL3149437)	0.49	3/20
SCHEMBL3657617	0.44	3/20
SCHEMBL3654752	0.43	3/20
SCHEMBL3657615	0.41	3/20
Trimethadione (SCHEMBL28882)	0.41	3/20
SCHEMBL2353877	0.67	2/20
SCHEMBL2353879	0.67	2/20
SCHEMBL2291128	0.63	2/20
SCHEMBL2353547	0.56	2/20
SCHEMBL1436662	0.56	2/20

Clinical trials — most relevant to PRTN3 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
A Study of KRN23 in Pediatric Patients With X-linked Hypophosphatemic Rickets/Osteomalacia	PHASE3	COMPLETED
Fever and Neutropenia in Pediatric Oncology Patients	PHASE3	WITHDRAWN
Peptide Vaccinations to Treat Patients With Low-Risk Myeloid Cancers	PHASE2	COMPLETED
Biologic Correlative Taxotere/AC	PHASE2	COMPLETED
A Study Evaluating Megestrol Acetate Modulation in Hormone Receptor Positive Advanced Breast Cancer	PHASE2	UNKNOWN
Neutrophils as Prognostic Factors in Granulomatosis With Polyangiitis (Formerly Named Wegener's Granulomatosis)	nan	COMPLETED
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH)	nan	COMPLETED
The Classification and Cause of Leukodystrophies of Unknown Cause	nan	COMPLETED
Family Blood Pressure Program - GENOA	nan	COMPLETED
Family Blood Pressure Program - SAPPHIRe Network	nan	COMPLETED
Genetic Studies of Inflammatory Bowel Disease	nan	COMPLETED
Molecular Changes and Biomarkers in Chronic Myeloproliferative Disorders	nan	COMPLETED
Family Blood Pressure Program - HyperGEN	nan	COMPLETED
The Nosology and Etiology of Leukodystrophies of Unknown Causes	nan	COMPLETED
Clinical and Molecular Characterisation of Orofaciodigital Syndromes and Other Clinical Phenotypes Secondary to Mutations in the OFD1 Gene	nan	UNKNOWN
Chromosome 5Q Gene Variants and Asthma-Related Traits	nan	COMPLETED
Inflammatory Genomics in Human Carotid Artery Disease	nan	COMPLETED
Genetic Studies of Lysosomal Storage Disorders	nan	ENROLLING_BY_INVITATION
Diagnostic Study of Patients With Acute Lymphoblastic Leukemia or Acute Promyelocytic Leukemia	nan	ACTIVE_NOT_RECRUITING
Identification of an Asthma Susceptibility Gene on 3P	nan	COMPLETED
Linkage Study in Familial Pulmonary Fibrosis	nan	COMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases	nan	UNKNOWN
Characterization of Patients With Cardiomyopathy to Identify Critical Patients Candidates for Cardiac Transplantation	nan	RECRUITING
Family Blood Pressure Program - GenNet Network	nan	COMPLETED
Serum Betatrophin Levels and Its Influencing Factors in Patients With Hyperthyroidism	nan	UNKNOWN
Epidemiology of Gout in French Polynesia	nan	COMPLETED
Pathophysiology of Paget's Disease of Bone	nan	COMPLETED
NCF Gene & TNFSF4 in SLE Patients	nan	UNKNOWN
Genetic Basis of Abdominal Aortic Aneurysm	nan	COMPLETED
French National Cohort of Patients With PRSS1 Mutations	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a PRTN3 binder may also engage these)

Protein	Name	Similarity
Q61096	—	0.990	Q61096 →
P79204	—	0.984	P79204 →
P21842	—	0.980	P21842 →
P56435	—	0.979	P56435 →
CMA1	Chymase	0.975	landscape →
Q7JIG6	—	0.974	Q7JIG6 →
P52195	—	0.974	P52195 →
P51124	—	0.973	P51124 →
CTSG	Cathepsin G	0.972	landscape →
KLK14	Kallikrein-14	0.972	landscape →
Q9H2R5	—	0.972	Q9H2R5 →
KLK2	Kallikrein-2	0.971	landscape →
P20718	—	0.970	P20718 →
P17977	—	0.970	P17977 →
P50341	—	0.969	P50341 →
P28293	—	0.968	P28293 →
KLK3	Prostate-specific antigen	0.968	landscape →
Q6UWY2	—	0.967	Q6UWY2 →
O46683	—	0.967	O46683 →
Q6IE59	—	0.967	Q6IE59 →
A7WPL7	—	0.967	A7WPL7 →
Q14B24	—	0.966	Q14B24 →
Q07276	—	0.966	Q07276 →
P33619	—	0.966	P33619 →
Q03238	—	0.966	Q03238 →
KLK5	Kallikrein-5	0.966	landscape →
Q8CGR5	—	0.965	Q8CGR5 →
P19236	—	0.965	P19236 →
O43240	—	0.965	O43240 →
P80219	—	0.964	P80219 →