Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.37 |
| ▸ | ARG1 | P05089 | 2/20 | 0.35 |
| ▸ | ARG2 | P78540 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HMGCR | P04035 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28726920 | 0.85 | KDM4E (0.44) | FFAR3LCKFYNKDM4EGLRA1 | |
| Acetic Acid SCHEMBL8516620 | 0.84 | FFAR3 (0.47) | FFAR3LCKFYNKDM4EGLRA1 | |
| Acetic Acid SCHEMBL319923 | 0.84 | FFAR3 (0.47) | FFAR3LCKFYNKDM4EGLRA1 | |
| Acetic Acid SCHEMBL3641038 | 0.84 | FFAR3 (0.47) | FFAR3LCKFYNKDM4EGLRA1 | |
| Acetic Acid SCHEMBL5710582 | 0.84 | FFAR3 (0.47) | FFAR3LCKFYNKDM4EGLRA1 | |
| Acetic Acid SCHEMBL9846828 | 0.81 | KDM4E (0.46) | FFAR3LCKFYNKDM4EGLRA1 | |
| Acetic Acid SCHEMBL28281534 | 0.81 | KDM4E (0.46) | FFAR3LCKFYNKDM4EGLRA1 | |
| Acetic Acid SCHEMBL27531087 | 0.81 | FFAR3 (0.44) | FFAR3LCKFYNKDM4EGLRA1 | |
| Acetic Acid SCHEMBL4404139 | 0.81 | KDM4E (0.46) | FFAR3LCKFYNKDM4EGLRA1 | |
| Acetic Acid SCHEMBL28212914 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050246828-A1 | Hygiene washing apparatus | PANASONIC CORPORATION (JP) | 2005-11-10 | — | — | US | disclosed |
| EP-1536075-A1 | HYGIENE WASHING APPARATUS | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2005-06-01 | — | — | EP | disclosed |