Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ARG1 | P05089 | 1/20 | 0.32 |
| ▸ | ARG2 | P78540 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GGT1 | P19440 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL3641038 | 1.00 | FFAR3 (0.47) | FFAR3LCKFYNKDM4EGLRA1 | |
| Acetic Acid SCHEMBL8516620 | 1.00 | FFAR3 (0.47) | FFAR3LCKFYNKDM4EGLRA1 | |
| Acetic Acid SCHEMBL9846828 | 0.84 | KDM4E (0.46) | FFAR3LCKFYNKDM4EGLRA1 | |
| Acetic Acid SCHEMBL4404139 | 0.84 | KDM4E (0.46) | FFAR3LCKFYNKDM4EGLRA1 | |
| Acetic Acid SCHEMBL6131040 | 0.84 | FFAR3 (0.44) | FFAR3LCKFYNKDM4EGLRA1 | |
| Acetic Acid SCHEMBL11140801 | 0.81 | FFAR3 (0.41) | FFAR3LCKFYNKDM4EGLRA1 | |
| Acetic Acid SCHEMBL28726920 | 0.81 | KDM4E (0.44) | FFAR3LCKFYNKDM4EGLRA1 | |
| Acetic Acid SCHEMBL5710582 | 0.80 | FFAR3 (0.47) | FFAR3LCKFYNKDM4EGLRA1 | |
| Acetic Acid SCHEMBL28664506 | 0.80 | FFAR3 (0.47) | FFAR3LCKFYNGLRA1SLC6A9 | |
| Acetic Acid SCHEMBL6662900 | 0.78 | FFAR3 (0.64) | FFAR3LCKFYNKDM4EGLRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590977-B1 | FLUORESCENT CARBAPENEMS | PFAENDLER HANS RUDOLF (DE) | 2022-06-29 | — | — | EP | disclosed |
| US-9969737-B2 | Fluorescent carbapenems | HANS RUDOLF PFAENDLER (DE) | 2018-05-15 | — | — | US | disclosed |
| US-20160251356-A1 | FLUORESCENT CARBAPENEMS | PFAENDLER HANS RUDOLF | 2016-09-01 | — | — | US | disclosed |
| US-9296752-B2 | Fluorescent carbapenems | Pfaendler, Hans R. (DE) | 2016-03-29 | — | — | US | disclosed |
| EP-2590977-A1 | FLUORESCENT CARBAPENEMS | Pfaendler, Hans Rudolf (DE) | 2013-05-15 | — | — | EP | disclosed |
| US-20130102017-A1 | FLUORESCENT CARBAPENEMS | Pfaendler, Hans Rudolf (DE) | 2013-04-25 | — | — | US | disclosed |
| WO-2012003955-A1 | FLUORESCENT CARBAPENEMS | PFAENDLER HANS RUDOLF (DE) | 2012-01-12 | — | — | WO | disclosed |
| EP-1732990-B1 | CATIONIC IMIDAZOLAZO DYES CONTAINING A 2,5-DIAMINOPHENYL MOIETY | BASF SE (DE) | 2011-09-07 | — | — | EP | disclosed |
| US-7482438-B2 | Cationic imidazolazo dyes containing a 2,5-diaminophenyl moiety | CIBA SPECIALTY CHEMICALS CORP. (US) | 2009-01-27 | — | — | US | disclosed |
| US-20070214580-A1 | Cationic Imidazolazo Dyes Containing A 2,5-Diaminophenyl | CIBA SPECIALTY CHEMICALS CORP. | 2007-09-20 | — | — | US | disclosed |
| CN-1965033-A | Cationic imidazolazo dyes containing a 2,5-diaminophenyl moiety | CIBA SC HOLDING AG (CH) | 2007-05-16 | — | — | CN | disclosed |
| EP-0732098-B1 | Polymerizable composition | DENTSPLY DETREY GMBH (DE) | 2002-06-05 | — | — | EP | disclosed |
| US-5688883-A | CATALYTIC POLYMERIZATION OF ACRYLATES FOR DENTAL SEALS OR ADHESIVES | DENTSPLY GMBH (DE) | 1997-11-18 | — | — | US | disclosed |
| EP-0732098-A2 | Polymerizable composition | DENTSPLY DETREY GmbH (DE) | 1996-09-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130102017-A1 | FLUORESCENT CARBAPENEMS | MGAM, MCRS1, ADSL | FFAR3 2162/4885LCK 4823/4885FYN 4811/4885 |
| US-20160251356-A1 | FLUORESCENT CARBAPENEMS | MGAM, MCRS1, ADSL | FFAR3 2162/4885LCK 4823/4885FYN 4811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.