Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKB | Q96GD4 | 17/20 | 0.79 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.78 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1061039 | 0.88 | HDAC1 (1.00) | AURKBHDAC1 | |
| SCHEMBL6131202 | 0.86 | HDAC1 (0.84) | AURKBHDAC1 | |
| SCHEMBL213280 | 0.85 | HDAC1 (0.85) | AURKBHDAC1 | |
| SCHEMBL8350666 | 0.84 | AURKB (0.78) | AURKBHDAC1LRRK2 | |
| SCHEMBL6919054 | 0.84 | AURKB (0.77) | AURKBHDAC1LRRK2 | |
| Lithium Ion SCHEMBL6919059 | 0.83 | AURKB (0.74) | AURKBHDAC1LRRK2 | |
| SCHEMBL1065095 | 0.83 | AURKB (0.79) | AURKBHDAC1LRRK2 | |
| SCHEMBL13713706 | 0.82 | HDAC1 (0.70) | AURKBHDAC1LRRK2 | |
| SCHEMBL213867 | 0.80 | HDAC1 (0.86) | AURKBHDAC1 | |
| SCHEMBL209760 | 0.79 | HDAC1 (0.85) | AURKBHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288282-A1 | Inhibitors of histone deacetylase | METHYLGENE, INC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288282-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC5, HDAC3 | AURKB 592/4885HDAC1 1/4885LRRK2 2421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.