Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1061039 | 0.91 | HDAC1 (1.00) | HDAC1AURKB | |
| SCHEMBL3552633 | 0.89 | HDAC1 (0.66) | HDAC1AURKB | |
| SCHEMBL213280 | 0.87 | HDAC1 (0.85) | HDAC1AURKB | |
| SCHEMBL6131078 | 0.86 | AURKB (0.79) | HDAC1AURKB | |
| SCHEMBL8350666 | 0.85 | AURKB (0.78) | HDAC1AURKB | |
| SCHEMBL6919054 | 0.84 | AURKB (0.77) | HDAC1AURKB | |
| SCHEMBL1065095 | 0.84 | AURKB (0.79) | HDAC1AURKB | |
| Lithium Ion SCHEMBL6919059 | 0.84 | AURKB (0.74) | HDAC1AURKB | |
| SCHEMBL213867 | 0.84 | HDAC1 (0.86) | HDAC1AURKB | |
| SCHEMBL209760 | 0.83 | HDAC1 (0.85) | HDAC1AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7868204-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2011-01-11 | — | — | US | disclosed |
| US-7868204-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2011-01-11 | — | — | US | disclosed |
| US-7838520-B2 | Inhibitors of histone deacetylase | METHYLGENE, INC. (CA) | 2010-11-23 | — | — | US | disclosed |
| US-7838520-B2 | Inhibitors of histone deacetylase | METHYLGENE, INC. (CA) | 2010-11-23 | — | — | US | disclosed |
| US-7595343-B2 | Inhibitors of histone deacetylase | METHYLGENE, INC. (CA) | 2009-09-29 | — | — | US | disclosed |
| US-7595343-B2 | Inhibitors of histone deacetylase | METHYLGENE, INC. (CA) | 2009-09-29 | — | — | US | disclosed |
| US-6897220-B2 | Inhibitors of histone deacetylase | METHYLGENE, INC. (CA) | 2005-05-24 | — | — | US | disclosed |
| WO-2004069823-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2004-08-19 | — | — | WO | disclosed |
| WO-2003024448-A2 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2003-03-27 | — | — | WO | disclosed |