Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL154641 | 0.92 | TSHR (0.54) | TSHRTDP1GPR84FFAR1ABCB1 | |
| SCHEMBL1871016 | 0.92 | TSHR (0.54) | TSHRTDP1GPR84FFAR1ABCB1 | |
| SCHEMBL671482 | 0.91 | TSHR (0.57) | TSHRTDP1GPR84FFAR1ABCB1 | |
| SCHEMBL8771126 | 0.91 | TSHR (0.57) | TSHRTDP1GPR84FFAR1ABCB1 | |
| SCHEMBL1171468 | 0.89 | TDP1 (0.53) | TSHRTDP1ALDH1A1CA1MAPT | |
| SCHEMBL1685294 | 0.87 | TSHR (0.51) | TSHRTDP1GPR84FFAR1CA1 | |
| Decylacetate SCHEMBL21837279 | 0.81 | TSHR (0.48) | TSHRGPR84FFAR1ALDH1A1MAPT | |
| SCHEMBL9323925 | 0.80 | TSHR (0.46) | TSHRTDP1GPR84FFAR1ALDH1A1 | |
| SCHEMBL5403623 | 0.79 | TSHR (0.49) | TSHRGPR84FFAR1ABCB1ZDHHC7 | |
| SCHEMBL4957257 | 0.79 | TSHR (0.54) | TSHRTDP1FFAR1ABCB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050136022-A1 | Cyclic siloxane compositions for the release of active ingredients | MOMENTIVE PERFORMANCE MATERIALS INC. | 2005-06-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050136022-A1 | Cyclic siloxane compositions for the release of active ingredients | F9, RPL39, ECPAS | TSHR 4528/4885TDP1 3632/4885GPR84 651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.